Results 91 to 100 of about 25,095 (239)

Exploring Ectoine Production From Methanol, Formate, and Electrochemically Produced Formate by Methyloligella halotolerans

open access: yesEngineering in Life Sciences, Volume 26, Issue 1, January 2026.
ABSTRACT Microbial synthesis using renewable C1‐carbon sources like electrochemically produced formate (e‐formate) represents a promising approach for climate‐neutral chemical production. This study investigates formate utilization for ectoine biosynthesis by the halophilic methylotroph Methyloligella halotolerans.
Aykut Kas   +5 more
wiley   +1 more source

IL21—STAT3 controls the pentose phosphate pathway to support metabolic reprogramming and tumor progression in chronic lymphocytic leukemia

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract Studying how microenvironmental cues influence metabolic reprogramming can uncover mechanisms driving tumor progression. Using an in vitro model with proliferative stimuli of the in vivo lymph node niche (LN)—including interleukin‐21 (IL‐21)—we examined metabolic rewiring in chronic lymphocytic leukemia (CLL) cells. We found that the metabolic
Rosita Del Prete   +16 more
wiley   +1 more source

Elucidation of Sulforaphane‐Mediated Effects on the Cellular Human Metabolome Using Metabolic Profiling

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Sulforaphane (SFN) is an isothiocyanate derived from broccoli and is related to various health‐promoting effects. By using metabolic profiling on the hepatoblastoma cell line HepG2 several effects on pathways such as TCA cycle, urea cycle and redox metabolism through SFN were identified.
Nadine Bieß   +3 more
wiley   +1 more source

Cross‐Feeding of Carbon and Nitrogen Between Aquificales and Thermus in Hot Springs

open access: yesEnvironmental Microbiology, Volume 28, Issue 1, January 2026.
Pampinifervens and Thermus populations are co‐distributed in hot springs in Yellowstone and Iceland. Genome reconstruction suggests Pampinifervens Flu05 cross feeds Thermus organic carbon and nitrogen, a phenomenon that was verified via co‐culture studies.
Lisa M. Keller   +3 more
wiley   +1 more source

Impact of Copper on the Physiology and Transcriptome of Methylosinus Trichosporium OB3b Grown on Either Methane or Methanol

open access: yesEnvironmental Microbiology, Volume 28, Issue 1, January 2026.
Methylosinus trichosporium OB3b can grow on methanol in the absence but not presence of copper due: (1) overgeneration of reducing power from methanol oxidation; (2) formate accumulation leading to acidification of the growth medium and inactivation of formate dehydrogenase; and (3) lack of expression of potential oxidative stress defence genes ...
Peng Peng, Jeremy D. Semrau
wiley   +1 more source

Conserved spatial patterning of gene expression in independent lineages of C4 plants

open access: yesNew Phytologist, Volume 249, Issue 1, Page 24-38, January 2026.
Summary C4 photosynthesis enhances carbon fixation efficiency by reducing photorespiration through the use of an oxygen‐insensitive carboxylase and spatial separation of photosynthesis between mesophyll and bundle sheath cells. The C4 pathway has evolved independently in > 60 plant lineages, but molecular mechanisms underpinning this convergence remain
Tianshu Sun   +4 more
wiley   +1 more source

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