Results 191 to 200 of about 5,220,302 (284)

Expression of Active Apurinic Apyrimidinic Endodeoxyribonuclease 1 in Human Platelets. [PDF]

FASEB J
Parolini I, Bellina A, Carpi G, Diatlova EA, Lippe G, Fontanini E, Barillari G, Isola M, Beltrami AP, Tell G.   +9 more
europepmc   +1 more source

Dyotropic Rearrangement of Hypervalent Iodine Species: Migrative Heterofunctionalization of Quaternary Carbons

Angewandte Chemie, EarlyView.
1,2‐Aryl migration involving in situ‐generated alkyl iodine(III) species proceeds through a previously unrecognized 1,2‐C/I(III) dyotropic rearrangement. Migratory aryl fluorination, acetoxylation, and alkoxylation of 2‐alkyl‐2‐aryl‐3‐iodopropanoates provide α‐heterofunctionalized products, accompanied by aryl migration from the α‐ to the β‐position ...
Chen‐Xu Liu, Qian Wang, Matthew D. Wodrich, Jieping Zhu   +3 more
wiley   +1 more source

Loss of EMILIN-1/integrin axis drives microenvironmental reprogramming in gastric tumorigenesis. [PDF]

Gastric Cancer
Capuano A, Vescovo M, Muzzin S, Timis E, Cesaratto L, Pivetta E, Doliana R, Palumbo A, Cannizzaro R, Canzonieri V, Scanziani E, Canesi S, Baldassarre G, Mongiat M, Spessotto P.   +14 more
europepmc   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +1 more source

Cross-Cultural Validation of POSAS 3.0: A Call for Methodologically Appropriate Approaches. [PDF]

Int Wound J
Vercelli S, Bravini E, Negrini F, Ferriero G.   +3 more
europepmc   +1 more source

Up to 16% Optical Carbon‐13 Hyperpolarization of Donor–Acceptor Molecules at 14.1 T

Angewandte Chemie, EarlyView.
Up to 16% 13C nuclear polarization is achieved using a rationally designed photo‐CIDNP polarizing agent (PA) in magic‐angle‐spinning NMR experiments at 14.1 T. The PA was designed using a combination of theoretical photocycle calculations and magnetic field dependent experiments to identify important new design principles.
Marcel Levien, Máté Visegrádi, Ganesan Karthikeyan, Gilles Casano, Christian Reiter, Sebastian Wegner, Armin Purea, Michael R. Wasielewski, Federico De Biasi, Olivier Ouari, Lyndon Emsley   +10 more
wiley   +1 more source

Common genomic and transcriptomic signatures in Richter transformation highlight druggable vulnerabilities and guide drug repurposing strategies. [PDF]

Leukemia
Vallone FE, Omezzolli G, Micillo M, Iannello A, Ferrero G, Berrino E, Mereu E, Bellomo SE, Rosso E, Di Napoli A, Jaksic O, Molinaro L, Marchiò C, Piva R, Cordero F, Deaglio S, Vaisitti T.   +16 more
europepmc   +1 more source

Il" Benessere" come problema di ricerca educativa

, 2016
BINANTI, Luigino, Il benessere come problema di ricerca educativa   +1 more
core  

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

Angewandte Chemie, EarlyView.
The paper describes the serendipitous discovery of chemical manipulation allowing the activator‐to‐inhibitor switching in Kv7.2 channel modulators. The molecular determinants driving this switch have been rationalized by multidisciplinary investigation encompassing synthetic and analytical chemistry, in silico methods, cryo‐EM analysis ...
Tania Ciaglia, Giusy Carleo, Zhenni Yang, Francesca Di Matteo, Federica De Rosa, Gerardina Smaldone, Zhao‐Bing Gao, Marco D'Alì, Rita Turcio, Demin Ma, Veronica Di Sarno, Nannan Su, Salvatore Vincenzo Giofrè, Giacomo Pepe, Pietro Campiglia, Alessia Bertamino, Francesco Miceli, Jiangtao Guo, Nunzio Iraci, Carmine Ostacolo, Maurizio Taglialatela   +20 more
wiley   +1 more source

<i>Mycobacterium chelonae</i> as an Underrecognized Cause of Granulomatous Disease in Fish and Humans: A Molecular One Health Study. [PDF]

Pathogens
Cubeddu T, Pilloni L, Burrai GP, Sanna MA, Polinas M, Murgia C, Gerosa C, Ambu R, Fanni D, Antuofermo E.   +9 more
europepmc   +1 more source