Results 141 to 150 of about 207,842 (296)

Author Response: Habitat loss weakens the positive relationship between grassland plant richness and above-ground biomass

Yongzhi Yan, Scott Jarvie, Qing Zhang
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Structural characteristics mediate forest mitigation potential against climate change and biodiversity loss. [PDF]

Ecol Appl
Lunow J, Burrascano S, Balducci L, Chianucci F, Chojnacki L, Doerfler I, Hofmeister J, Hošek J, Ódor P, Schall P, Sitzia T, Simons NK.   +11 more
europepmc   +1 more source

Intraspecific trait variation drives grassland species richness and productivity under changing precipitation

, 2021
Meifeng Deng
openalex   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Influences of Structural and Species Diversity on Forest Resistance to Drought. [PDF]

Ecol Lett
Crockett ETH, Guo Q, Atkins JW, Sun G, Potter KM, Costanza JK, Ollinger SV, Woodall CW, McNulty S, Trettin C, Holgerson J, Xiao J.   +11 more
europepmc   +1 more source

Measuring overall functional diversity by aggregating its multiple facets: Functional richness, biomass evenness, trait evenness and dispersion [PDF]

Laurie Anne Wojcik, Ursula Gaedke, Ellen van Velzen, Toni Klauschies   +3 more
openalex   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Estimating global bee species richness and taxonomic gaps. [PDF]

Nat Commun
Dorey JB, Gilpin AM, Johnston NP, Esquerré D, Hughes AC, Ascher JS, Orr MC.   +6 more
europepmc   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source