Results 61 to 70 of about 431,549 (313)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2000 Recent research has shown that rich' households save at much higher rates than others (see Carroll (2000); Dynan, Skinner, and Zeldes (1996); Gentry and Hubbard (1998); Huggett (1996); Quadrini (1999)). This paper documents another large difference between the rich and the rest of the population: portfolios of the rich are heavily skewed toward risky ...
openaire +3 more sources
Perception is rich and probabilistic
Scientific Reports, 2022 Abstract When we see a stimulus, e.g. a star-shaped object, our intuition is that we should perceive a single, coherent percept (even if it is inaccurate). But the neural processes that support perception are complex and probabilistic. Simple lines cause orientation-selective neurons across a population to fire in a probabilistic-like
Syaheed B. Jabar, Daryl Fougnie
openaire +3 more sources
, 2018 We examined how both horizontal and vertical aspects of land-cover diversity influence patterns of avian species-richness across North America. Using count data from Breeding Bird Survey routes within the conterminous USA and land-cover data from the ...
John B. Dunning Jr. (3811522) +2 more
core +1 more source
Zoologia (Curitiba), 2011 This study records and analyzes the diversity and structure of a snake assemblage in a transition area between Cerrado and Caatinga, in the municipality of Castelo do Piauí, state of Piauí, comparing the distribution and similarity of the species ...
Francílio da Silva Rodrigues +1 more
doaj +1 more source
Effect of physiographical factors on tree species diversity (case study: Kandelat Forest Park) [PDF]
تحقیقات جنگل و صنوبر ایران, 2013 In order to identify the diversity of tree species in relation to physiographic factors (elevation, aspect and slope), the Kandelat Forest Park with an area of 614.85 hectare was surveyed, where is located southeast of Rasht city.
Hasan Pourbabaei, Tahereh Haghgooy
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Tryptophan-Rich and Proline-Rich Antimicrobial Peptides [PDF]
Molecules, 2018 Due to the increasing emergence of drug-resistant pathogenic microorganisms, there is a world-wide quest to develop new-generation antibiotics. Antimicrobial peptides (AMPs) are small peptides with a broad spectrum of antibiotic activities against bacteria, fungi, protozoa, viruses and sometimes exhibit cytotoxic activity toward cancer cells. As a part
Awdhesh Mishra +3 more
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source