Results 61 to 70 of about 358,830 (316)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Tryptophan-Rich and Proline-Rich Antimicrobial Peptides [PDF]
Molecules, 2018 Due to the increasing emergence of drug-resistant pathogenic microorganisms, there is a world-wide quest to develop new-generation antibiotics. Antimicrobial peptides (AMPs) are small peptides with a broad spectrum of antibiotic activities against bacteria, fungi, protozoa, viruses and sometimes exhibit cytotoxic activity toward cancer cells. As a part
Awdhesh Mishra +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Determinants of species richness patterns in the Netherlands across multiple taxonomic groups
, 2009 We examined the species richness patterns of five different species groups (mosses, reptiles and amphibians, grasshoppers and crickets, dragonflies, and hoverflies) in the Netherlands (41,500 km2) using sampling units of 5 × 5 km. We compared the spatial
Barendrecht, A. +3 more
core +1 more source
, 2021 The Forest Stewardship Council (FSC) forest certification was introduced in Nepal with an assumption that it improves forests and ecosystem services while addressing the drivers of forest degradation.
Joshi, Nabin Raj +4 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sociobiology, 2013 Although bees are important pollinators in several ecosystems around the world, studies on bee diversity in hygrophilous forests are scarce. This type of vegetation is restricted to permanently wet soils and, therefore, has particular floristic ...
Maurício Meirelles do Nascimento Castro +3 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Sample richness and genetic diversity as drivers of chimera formation in nSSU metagenetic analyses [PDF]
, 2012 Eukaryotic diversity in environmental samples is often assessed via PCR-based amplification of nSSU genes. However, estimates of diversity derived from pyrosequencing environmental data sets are often inflated, mainly because of the formation of chimeric
Lallias, Delphine +12 more
core +1 more source
Gayana: Botanica, 2011 El propósito de este trabajo fue estudiar la continuidad ecológica en la Reserva Nacional Isla Mocha, mediante el conocimiento de la riqueza y frecuencia de líquenes epífitos en 14 parcelas distribuidas al azar al interior de la reserva.
ALEJANDRO GATICA +2 more
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