Results 51 to 60 of about 198,572 (266)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Although bees are important pollinators in several ecosystems around the world, studies on bee diversity in hygrophilous forests are scarce. This type of vegetation is restricted to permanently wet soils and, therefore, has particular floristic ...
Maurício Meirelles do Nascimento Castro +3 more
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
El propósito de este trabajo fue estudiar la continuidad ecológica en la Reserva Nacional Isla Mocha, mediante el conocimiento de la riqueza y frecuencia de líquenes epífitos en 14 parcelas distribuidas al azar al interior de la reserva.
ALEJANDRO GATICA +2 more
doaj
The Impact of Exotic Tamarix Species on Riparian Plant Biodiversity
This study investigated the impact of exotic Tamarix species on vascular plant biodiversity in riparian ecosystems in the Western Cape Province, South Africa.
Kgalalelo Tshimologo Annie Setshedi +1 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Concepția biblică privind bunăstarea
Man's natural concern for well-being is also found in biblical texts, even though the Scripture’s point of view differs somewhat from the prospects offered by the usual economic theories.
Dan Constantinescu
doaj
Namibia is a large country with a population slightly above 2 million of which 73% live in rural areas. It is the driest country in sub-Saharan Africa with unpredictable rainfall patterns which occur between October and May. The Cuvelai Etosha Basin is
Billy McBenedict +4 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

