Results 71 to 80 of about 198,572 (266)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Understory species richness in an urban forest fragment, Pernambuco, Brazil [PDF]

open access: yesBiotemas, 2009
This study characterizes the floristic composition of the understory of Parque Estadual de Dois Irmãos, (08°01’15.1”S and 34°56’3.2”W), an area of about 370ha characterized as a lowland ombrophilous dense forest.
Ana Cristina Ramos de Souza   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Caracterización biogeográfica de la Faja Volcánica Transmexicana y análisis de los patrones de distribución de su mastofauna Biogeographic characterization of the Transmexican Volcanic Belt and analysis of the distributional patterns of the mammal fauna

open access: yesRevista Mexicana de Biodiversidad, 2012
La provincia de la Faja Volcánica Transmexicana (FVT) está reconocida como centro de diversificación, endemismo y transición biogeográfica. Debido a su heterogeneidad ambiental, origen geológico complejo e intrincados patrones de distribución, aún no ...
Niza Gámez   +4 more
doaj  

Determinants of capture-recapture success: an evaluation of trapping methods to estimate population and community parameters for Atlantic forest small mammals

open access: yesZoologia (Curitiba), 2015
Efficiently obtaining high-quality data on animal populations and communities is paramount for ecological and conservation studies. In many instances these data come from live-trapping, the success of which depends on various factors, such as the ...
Camila S. Barros   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Reanálisis de la diversidad alfa: alternativas para interpretar y comparar información sobre comunidades ecológicas Reanalyzing alpha diversity: alternatives to understand and compare information about ecological communities

open access: yesRevista Mexicana de Biodiversidad, 2011
El índice de entropía de Shannon y otras medidas de complejidad se utilizan frecuentemente para evaluar la diversidad de especies en comunidades ecológicas, aun cuando su comprensión es difícil y sus valores no son comparables. En este trabajo se muestra
Claudia E. Moreno   +3 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

MBI: an R package for calculating multiple-site beta diversity indices [PDF]

open access: yesComputational Ecology and Software, 2013
Beta diversity is one of most important features in community ecology. Indices for pairwise comparison of beta diversity have been extensively developed, but the ones specifically designed for multiple-site comparison of beta diversity are still limited.
YouHua Chen
doaj  

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

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