Nitric Oxide Inhibition of Rickettsia rickettsii. [PDF]
Infect Immun, 2021 Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, is an enzootic, obligate, intracellular bacterial pathogen. Nitric oxide (NO) synthesized by the inducible NO synthase (iNOS) is a potent antimicrobial component of innate ...
Fitzsimmons LF, Clark TR, Hackstadt T.
europepmc +4 more sources
Development and validation of a novel detection method for Rickettsia rickettsii using a loop-mediated isothermal amplification assay. [PDF]
Front Microbiol, 2023 Introduction Rickettsia rickettsii is an obligate, intracellular pathogen and the causative agent of Rocky Mountain spotted fever (RMSF). RMSF is an important zoonotic disease due to its high fatal outcome in humans.
Carvajal-Gamez BI +7 more
europepmc +2 more sources
Identification of an autotransporter peptidase of Rickettsia rickettsii responsible for maturation of surface exposed autotransporters. [PDF]
PLoS Pathog, 2023 Members of the spotted fever group rickettsia express four large, surface-exposed autotransporters, at least one of which is a known virulence determinant.
Nock AM +10 more
europepmc +2 more sources
Susceptibility of Amblyomma sculptum, Vector of Rickettsia rickettsii, Ticks from a National Park and an Experimental Farm to Different Synthetic Acaricides. [PDF]
Pathogens, 2023 Amblyomma sculptum is a relevant tick species from a One Health perspective, playing an important role as a vector of Rickettsia rickettsii, the main agent of spotted fever rickettsiosis in Brazil. In this study, we evaluated the susceptibility of two A.
Cardoso ERN +17 more
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Immune Monitoring of Paediatric Patients Infected with Rickettsia rickettsii, Ehrlichia canis and Coinfected. [PDF]
Pathogens, 2022 In 2021, 273 Rocky Mountain spotted fever cases were reported nationwide in Mexico. In Chihuahua City, fourteen samples were obtained from children suspected of rickettsial infection.
Garcia-Rosales L +10 more
europepmc +2 more sources
Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture. [PDF]
mBio, 2022 The mechanism of actin-based motility of spotted fever group Rickettsia has been studied extensively, but here, we provide genetic evidence that motility is a regulated process in R. rickettsii.
Nock AM, Clark TR, Hackstadt T.
europepmc +2 more sources
Isolation of Rickettsia rickettsii in Rocky Mountain Spotted Fever Outbreak, Panama. [PDF]
Emerg Infect Dis, 2021 We report new cases of Rocky Mountain spotted fever in patients from Kinkantu, Ngäbe-Bugle indigenous comarca, Panama. We isolated Rickettsia rickettsii in cell culture after intraperitoneal inoculation of guinea pigs with tissues from a deceased patient.
Zaldívar Y +7 more
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Experimental infection of dogs with a Brazilian strain of Rickettsia rickettsii: clinical and laboratory findings [PDF]
Memorias do Instituto Oswaldo Cruz, 2008 The bacterium Rickettsia rickettsii is the etiological agent of an acute, severe disease called Rocky Mountain spotted fever in the United States or Brazilian spotted fever (BSF) in Brazil.
Eliane M Piranda +6 more
doaj +4 more sources
Rickettsia rickettsii and Rickettsia typhi in inhabitants from a rural community of southeast Mexico. [PDF]
Rev Peru Med Exp Salud Publica, 2022 -
Torres-Castro M +6 more
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Isolate-Dependent Differences in Clinical, Pathological, and Transcriptional Profiles following In Vitro and In Vivo Infections with Rickettsia rickettsii. [PDF]
Infect Immun, 2021 Rickettsia rickettsii, the etiological agent of Rocky Mountain spotted fever (RMSF), a life-threatening tick-borne disease that affects humans and various animal species, has been recognized in medicine and science for more than 100 years.
Galletti MFBM +5 more
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