Fatal Human Infection with Rickettsia rickettsii, Yucatán, Mexico
Emerging Infectious Diseases, 2006 The first fatal Rickettsia rickettsii infection was diagnosed in the southwest of Mexico. The patient had fever, erythematous rash, abdominal pain, and severe central nervous system involvement with convulsive crisis. The diagnosis of R.
Jorge E. Zavala-Castro +8 more
doaj +3 more sources
Nitric Oxide Inhibition of Rickettsia rickettsii. [PDF]
Infect Immun, 2021 Rickettsia rickettsii , the causative agent of Rocky Mountain spotted fever, is an enzootic, obligate, intracellular bacterial pathogen. Nitric oxide (NO) synthesized by the inducible NO synthase (iNOS) is a potent antimicrobial component of innate immunity and has been implicated in the control of virulent ...
Fitzsimmons LF, Clark TR, Hackstadt T.
europepmc +3 more sources
NF-κB Activation duringRickettsia rickettsiiInfection of Endothelial Cells Involves the Activation of Catalytic IκB Kinases IKKα and IKKβ and Phosphorylation-Proteolysis of the Inhibitor Protein IκBα [PDF]
Infection and Immunity, 2004 ABSTRACT Rickettsia rickettsii is an obligate intracellular pathogen that is the causative agent of Rocky Mountain spotted fever. To identify genes involved in the virulence of R. rickettsii , the genome of an avirulent strain, R.
Dawn R. Clifton +3 more
openalex +4 more sources
Experimental Infection of Amblyomma aureolatum Ticks with Rickettsia rickettsii
Emerging Infectious Diseases, 2011 We experimentally infected Amblyomma aureolatum ticks with the bacterium Rickettsia rickettsii, the etiologic agent of Rocky Mountain spotted fever (RMSF). These ticks are a vector for RMSF in Brazil. R.
Marcelo B. Labruna +8 more
doaj +3 more sources
Aerosol infection of monkeys with Rickettsia rickettsii. [PDF]
Bacteriological Reviews, 1966 S Saslaw, H N Carlisle
openalex +3 more sources
Pathogens, 2021 Rickettsia are significant sources of tick-borne diseases in humans worldwide. In North America, two species in the spotted fever group of Rickettsia have been conclusively associated with disease of humans: Rickettsia rickettsii, the causative agent of ...
M. Nathan Kristof +5 more
doaj +1 more source
Absorption of Rickettsia rickettsii antibodies by Rickettsia rickettsii antigens in four diagnostic tests [PDF]
Journal of Clinical Microbiology, 1983 Immunoabsorption profiles were determined for Rickettsia rickettsii antigens used in four confirmatory tests for detection of antibodies to Rocky Mountain spotted fever. A human serum reactive in the four tests was absorbed with each test antigen and then reexamined by all four tests.
K E, Hechemy +4 more
openaire +2 more sources
Laboratory Maintenance of Rickettsia rickettsii [PDF]
Current Protocols in Microbiology, 2008 AbstractThis unit includes protocols for the laboratory maintenance of the obligate intracellular bacterium Rickettsia rickettsii, including propagation in mammalian cell cultures, as well as isolation, counting, and storage procedures. Regulations for working with R. rickettsii in biosafety level 3 containment are also discussed. Curr.
Nicole C, Ammerman +2 more
openaire +2 more sources
Development of a rapid and visual detection method for Rickettsia rickettsii combining recombinase polymerase assay with lateral flow test. [PDF]
PLoS One, 2018 Qi Y +11 more
europepmc +3 more sources
Experimental infection of horses with Rickettsia rickettsii. [PDF]
Parasit Vectors, 2016 Rickettsia rickettsii is vectored by ticks, and some vertebrate hosts can be sources of infection to ticks during bacteremic periods. In Brazil, the main vector for R. rickettsii is the tick Amblyomma sculptum, a member of the A. cajennense complex. Horses, in turn, are one of the major hosts for A. sculptum.
Ueno TE +5 more
europepmc +4 more sources