Results 21 to 30 of about 7,697 (229)

Intranuclear growth of Rickettsia rickettsii [PDF]

Journal of Bacteriology, 1968
Willy Burgdorfer, R. L. Anacker, R.G. Bird, D. S. Bertram   +3 more
openalex   +4 more sources

Selective fragmentation of the trans-Golgi apparatus by Rickettsia rickettsii. [PDF]

PLoS Pathog, 2020
Fragmentation of the Golgi apparatus is observed during a number of physiological processes including mitosis and apoptosis, but also occurs in pathological states such as neurodegenerative diseases and some infectious diseases. Here we show that highly virulent strains of Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever ...
Aistleitner K, Clark T, Dooley C, Hackstadt T.   +3 more
europepmc   +6 more sources

<i>Rickettsia rickettsii</i> RoaM negatively regulates expression of a limited number of rickettsial genes. [PDF]

mSphere
Nock AM, Clark TR, Anzick SL, Meyer EA, Miller R, Holbrook MG, Ricklefs S, Martens C, Lack J, Hackstadt T.   +9 more
europepmc   +2 more sources

Core-genome guided novel therapeutic targets identification and chimeric vaccine designing against Rickettsia rickettsii. [PDF]

Sci Rep
Arshad F, Sarfraz A, Shehroz M, Nishan U, Perveen A, Ullah R, Ibrahim MA, Shah M.   +7 more
europepmc   +2 more sources

Autophagy facilitates intracellular survival of pathogenic rickettsiae in macrophages via evasion of autophagosomal maturation and reduction of microbicidal pro-inflammatory IL-1 cytokine responses

Microbiology Spectrum, 2023
The genus Rickettsia is comprised of obligate intracellular bacterial parasites of a wide range of arthropod and vertebrate hosts. Some Rickettsia species (spp.) are responsible for serious human diseases globally.
Oliver H. Voss, Hodalis Gaytan, Saif Ullah, Mohammad Sadik, Imran Moin, M. Sayeedur Rahman, Abdu F. Azad   +6 more
doaj   +1 more source

Hosts mobility and spatial spread of Rickettsia rickettsii. [PDF]

PLoS Comput Biol, 2018
There are a huge number of pathogens with multi-component transmission cycles, involving amplifier hosts, vectors or complex pathogen life cycles. These complex systems present challenges in terms of modeling and policy development. A lethal tick-borne infectious disease, the Brazilian Spotted Fever (BSF), is a relevant example of that.
Polo G, Mera Acosta C, Labruna MB, Ferreira F, Brockmann D.   +4 more
europepmc   +8 more sources

Experimental infection of horses with Rickettsia rickettsii. [PDF]

Parasit Vectors, 2016
Rickettsia rickettsii is vectored by ticks, and some vertebrate hosts can be sources of infection to ticks during bacteremic periods. In Brazil, the main vector for R. rickettsii is the tick Amblyomma sculptum, a member of the A. cajennense complex. Horses, in turn, are one of the major hosts for A. sculptum.
Ueno TE, Costa FB, Moraes-Filho J, Agostinho WC, Fernandes WR, Labruna MB.   +5 more
europepmc   +5 more sources

Absorption of Rickettsia rickettsii antibodies by Rickettsia rickettsii antigens in four diagnostic tests [PDF]

Journal of Clinical Microbiology, 1983
Immunoabsorption profiles were determined for Rickettsia rickettsii antigens used in four confirmatory tests for detection of antibodies to Rocky Mountain spotted fever. A human serum reactive in the four tests was absorbed with each test antigen and then reexamined by all four tests.
Hassan A. Gaafar, Karim E. Hechemy, N L Carlo, R L Anacker, John A. Fox   +4 more
openaire   +3 more sources

Significant Growth by Rickettsia Species within Human Macrophage-Like Cells Is a Phenotype Correlated with the Ability to Cause Disease in Mammals

Pathogens, 2021
Rickettsia are significant sources of tick-borne diseases in humans worldwide. In North America, two species in the spotted fever group of Rickettsia have been conclusively associated with disease of humans: Rickettsia rickettsii, the causative agent of ...
M. Nathan Kristof, Paige E. Allen, Lane D. Yutzy, Brandon Thibodaux, Christopher D. Paddock, Juan J. Martinez   +5 more
doaj   +1 more source

Plaque Assay for Rickettsia rickettsii [PDF]

Journal of Bacteriology, 1969
A plaque technique for the assay of Rickettsia rickettsii is described. The method employs primary chick or green monkey kidney monolayer cell cultures with either an agarose or special Noble agar overlay. Plaques were counted in 6 days and resultant titers correlated well with ld 50
Edmund H. Weinberg, Jack R. Stakebake, Peter J. Gerone   +2 more
openalex   +4 more sources