Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture [PDF]
mBio, 2022 The mechanism of actin-based motility of spotted fever group Rickettsia has been studied extensively, but here, we provide genetic evidence that motility is a regulated process in R. rickettsii.
A. Nock, Tina Clark, T. Hackstadt
semanticscholar +2 more sources
Isolation of Rickettsia rickettsii in Rocky Mountain Spotted Fever Outbreak, Panama [PDF]
Emerg Infect Dis, 2021 We report new cases of Rocky Mountain spotted fever in patients from Kinkantu, Ngäbe-Bugle indigenous comarca, Panama. We isolated Rickettsia rickettsii in cell culture after intraperitoneal inoculation of guinea pigs with tissues from a deceased patient.
Yamitzel Zaldívar +7 more
semanticscholar +2 more sources
Isolate-Dependent Differences in Clinical, Pathological, and Transcriptional Profiles following In Vitro and In Vivo Infections with Rickettsia rickettsii [PDF]
Infect Immun, 2021 Rickettsia rickettsii, the etiological agent of Rocky Mountain spotted fever (RMSF), a life-threatening tick-borne disease that affects humans and various animal species, has been recognized in medicine and science for more than 100 years.
M. F. Galletti +5 more
semanticscholar +2 more sources
Development and validation of a novel detection method for Rickettsia rickettsii using a loop-mediated isothermal amplification assay [PDF]
Front Microbiol, 2023 Introduction Rickettsia rickettsii is an obligate, intracellular pathogen and the causative agent of Rocky Mountain spotted fever (RMSF). RMSF is an important zoonotic disease due to its high fatal outcome in humans.
B. I. Carvajal-Gamez +7 more
semanticscholar +2 more sources
Survey of vector-borne agents in feral cats and first report of Babesia gibsoni in cats on St Kitts, West Indies [PDF]
BMC Veterinary Research, 2017 Background As there is little data on vector-borne diseases of cats in the Caribbean region and even around the world, we tested feral cats from St Kitts by PCR to detect infections with Babesia, Ehrlichia and spotted fever group Rickettsia (SFGR) and ...
Patrick John Kelly +8 more
doaj +3 more sources
Experimental infection of horses with Rickettsia rickettsii [PDF]
Parasites & Vectors, 2016 Rickettsia rickettsii is vectored by ticks, and some vertebrate hosts can be sources of infection to ticks during bacteremic periods. In Brazil, the main vector for R. rickettsii is the tick Amblyomma sculptum, a member of the A. cajennense complex. Horses, in turn, are one of the major hosts for A. sculptum.
Francisco B. Costa +5 more
openaire +4 more sources
Clinical manifestations of Rickettsia rickettsii in a familial outbreak in Panama.
Travel Medicine and Infectious Disease, 2023 We report an isolated outbreak of Rickettsia rickettsii in the Ngäbe-Buglé indigenous region, located 750 m (tropical wet) above sea level, in a jungle and mountainous area of Western Panama. Seven members of a family were infected simultaneously, resulting in four deaths.
C. Daza T +11 more
semanticscholar +3 more sources
Rickettsia rickettsii virulence determinants RARP2 and RapL mitigate IFN-β signaling in primary human dermal microvascular endothelial cells [PDF]
mBioWe compared the growth characteristics of a virulent Rickettsia rickettsii strain (Sheila Smith) to an attenuated R. rickettsii stain (Iowa) and a non-pathogenic species (R.
Liam Fitzsimmons +3 more
semanticscholar +2 more sources
Study of infection by Rickettsiae of the spotted fever group in humans and ticks in an urban park located in the City of Londrina, State of Paraná, Brazil [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2011 INTRODUCTION: Spotted fevers are emerging zoonoses caused by Rickettsia species in the spotted fever group (SFG). Rickettsia rickettsii is the main etiologic agent of Brazilian spotted fever (BSF) and it is transmitted by Amblyomma spp. ticks.
Roberta Santos Toledo +7 more
doaj +4 more sources
Comparative Analysis of Infection by Rickettsia rickettsii Sheila Smith and Taiaçu Strains in a Murine Model [PDF]
Pathogens, 2020 Rocky Mountain spotted fever (RMSF) is a life-threatening tick-borne disease caused by Rickettsia rickettsii, which is widely distributed throughout the Americas.
E. Esteves +7 more
semanticscholar +2 more sources