Results 41 to 50 of about 21,258 (244)

MicroRNA Signature of Human Microvascular Endothelium Infected with Rickettsia rickettsii [PDF]

International Journal of Molecular Sciences, 2017
MicroRNAs (miRNAs) mediate gene silencing by destabilization and/or translational repression of target mRNA. Infection of human microvascular endothelial cells as primary targets of Rickettsia rickettsii, the etiologic agent of Rocky Mountain spotted fever, triggers host responses appertaining to alterations in cellular gene expression.
Jignesh Patel, Abha Sahni, Hema P. Narra, Sanjeev K. Sahni   +3 more
openaire   +4 more sources

Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever. [PDF]

Am J Trop Med Hyg, 2019
Rocky Mountain spotted fever (RMSF), caused by Rickettsia rickettsii, is a severe tick-borne infection endemic to the Americas. Oral doxycycline is effective, but during severe life-threatening disease, intravenous therapy is recommended.
L. Blanton, N. Wilson, B. Quade, D. Walker   +3 more
semanticscholar   +2 more sources

Transmission dynamics and control of Rickettsia rickettsii in populations of Hydrochoerus hydrochaeris and Amblyomma sculptum

PLoS Neglected Tropical Diseases, 2017
Background Brazilian Spotted Fever (BSF), caused by the bacterium Rickettsia rickettsii, is the tick-borne disease that generates the largest number of human deaths in the world. In Brazil, the current increase of BSF human cases has been associated with
Gina Polo, Carlos Mera Acosta, Marcelo B. Labruna, Fernando Ferreira   +3 more
openalex   +3 more sources

Modelos potenciales de distribución geográfica y climática del complejo Amblyomma cajennense (Acari: Ixodidae), potencial vector de Rickettsia rickettsii en Colombia

Biomedica : revista del Instituto Nacional de Salud, 2018
Introducción. Las especies del complejo Amblyomma cajennense, potenciales vectores implicados en la transmisión de Rickettsia rickettsii en Centroamérica y Suramérica, presentan una amplia distribución geográfica en el neotrópico. En Colombia, todavía es
Leidy Y. Acevedo-Gutiérrez, Luís E. Paternina, Andrés F. Londoño, Gabriel Parra-Henao, Juan David Rodas   +4 more
openalex   +3 more sources

Evaluation of changes to the Rickettsia rickettsii transcriptome during mammalian infection [PDF]

PLOS ONE, 2017
The lifecycle of Rickettsia rickettsii includes infection of both mammalian and arthropod hosts, with each environment presenting distinct challenges to survival. As such, these pathogens likely have distinctive transcriptional strategies for infection of each host.
Riley, Sean, Pruneau, Ludovic, Martinez, Juan   +2 more
openaire   +6 more sources

Amblyomma sculptum Salivary PGE2 Modulates the Dendritic Cell-Rickettsia rickettsii Interactions in vitro and in vivo [PDF]

Front Immunol, 2019
Amblyomma sculptum is an important vector of Rickettsia rickettsii, causative agent of Rocky Mountain spotted fever and the most lethal tick-borne pathogen affecting humans. To feed on the vertebrate host's blood, A. sculptum secretes a salivary mixture,
E. Esteves, Bruna Bizzarro, F. Costa, Alejandro Ramírez-Hernández, A. Peti, A. D. Cataneo, P. F. Wowk, R. P. Timóteo, M. Labruna, P. I. Silva Júnior, C. L. Silva, L. Faccioli, Andréa C Fogaça, C. Sorgi, A. Sá-Nunes   +14 more
semanticscholar   +2 more sources

Rickettsia rickettsii Whole-Cell Antigens Offer Protection against Rocky Mountain Spotted Fever in the Canine Host [PDF]

Infect Immun, 2018
Rocky Mountain spotted fever (RMSF) is a potentially fatal tick-borne disease in people and dogs. RMSF is reported in the United States and several countries in North, Central, and South America.
A. Alhassan, Huitao Liu, J. McGill, A. Cerezo, L. U. Jakkula, Arathy D. S. Nair, Emma Winkley, Sally Olson, D. Marlow, Abha Sahni, H. Narra, S. Sahni, J. Henningson, R. Ganta   +13 more
semanticscholar   +2 more sources

Rickettsia rickettsiiinAmblyomma patinoiTicks, Colombia [PDF]

Emerging Infectious Diseases, 2015
Para el editor: Rickettsia rickettsii es el agente etiológico de la fiebre maculosa de las Montañas Rocosas (RMSF), una rickettsiosis transmitida por garrapatas altamente letal restringida al hemisferio occidental (1,2). En Colombia, R. rickettsii se informó por primera vez durante la década de 1930, cuando 62 (95%) de 65 personas afectadas murieron de
Álvaro A. Faccini‐Martínez, Francisco B. Costa, Tatiana E. Hayama-Ueno, Alejandro Ramírez-Hernández, Jesús A. Cortés-Vecino, Marcelo B. Labruna, Marylin Hidalgo   +6 more
openaire   +5 more sources

Development of a rapid and visual detection method for Rickettsia rickettsii combining recombinase polymerase assay with lateral flow test [PDF]

PLoS One, 2018
Objectives Rickettsia rickettsii is the causative agent of Rocky Mountain spotted fever, which is the most severe spotted fever group (SFG) rickettsiosis. Developing a simple and reliable detection method is required.
Y. Qi, Yinxiu Shao, J. Rao, Wanpeng Shen, Qiong Yin, Xiaoling Li, Hongxia Chen, Jiameng Li, Wenwen Zeng, Shulong Zheng, Suyun Liu, Yuexi Li   +11 more
semanticscholar   +2 more sources

Intranuclear growth of Rickettsia rickettsii [PDF]

Journal of Bacteriology, 1968
Willy Burgdorfer, R. L. Anacker, R.G. Bird, D. S. Bertram   +3 more
openalex   +4 more sources