Results 61 to 70 of about 195,993 (291)

Collective creative etude in developing literary education

Теоретическая и экспериментальная психология
Вackground. The article is devoted to one of the organizational forms of teaching created for a fundamentally new course of literature at school. The course was developed by G.N. Kudina and Z.N.
Zinaida N. Novlyanskaya
doaj   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Riddle in Ancient Iran: Riddle Debate in the Matikan-e Yusht Faryan

Şarkiyat Mecmuası
The riddle, a literary genre with ancient roots, persists in both oral and written tradition to this day. Its presence in Iranian literature can also be traced to ancient times.
Yaşar Yeşim Amaç
doaj   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

ANIMAL PREDATORS AS A CHARACTERISING ELEMENT IN SHORT FOLKLORE FORMS

Proverbium
Language reflects how we perceive our surroundings. Not only does it enable us to describe them but we also use linguistic expressions to express our ideas metaphorically.
Saša Babič
doaj   +1 more source

US Political Leadership and Crisis Communication During COVID-19

Cogent Social Sciences, 2021
The research explored the role of political leadership in response to the novel coronavirus (COVID-19). The researchers conducted a political discourse analysis on 239 transcripts from the press briefings of President Trump and seven U.S.
Daryl V. Watkins, Aaron D. Clevenger
doaj   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

The Riddle of Gravitation [PDF]

, 2011
There is no doubt that both the special and general theories of relativity capture the imagination. The anti-intuitive properties of the special theory of relativity and its deep philosophical implications, the bizzare and dazzling predictions of the ...
Sid-Ahmed, A. M.
core  

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source

Wittgenstein i zagadka Anzelma [PDF]

Analiza i Egzystencja, 2013
The paper is devoted to the problem of the two paradoxes: the paradox of absolute value in Wittgenstein’s Lecture on Ethics and the paradox of Anselm’s Name of God from the Proslogion.
Jakub Gomułka
doaj