Results 71 to 80 of about 195,993 (291)

The Economic impact of Florida's recreational boating industry in 1985 [PDF]

, 1987
The recreational boating industry is an important component of Florida's economy. Previous Florida Sea Grant College supported research has documented this economic importance to the state's economy in 1980 (see Milon and Riddle, 1983, and Milon et al ...
Adams, Charles M., Minton, J. Walter
core  

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

Advanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang, Dongpeng Jiang, Peng Ke, Xiaosen Bian, Lili Zhang, Ying Zhang, Tingting Zhu, Weiwei Qu, Wenhui Qi, Yang Xu, Chengcheng Fu, Depei Wu, Jianhong Chu   +12 more
wiley   +1 more source

Maironio mįslė | Enigma of Maironis [PDF]

Literatūra (Vilnius), 2013
One strophe of the Lithuanian poetry patriarch Maironis is analysed in the article. Firstly, attention is drawn to some Lithuanian mythological notions used in the strophe, namely of the Sun as a personified heavenly queen, of the dawn as woven fabric ...
Dainius Razauskas
doaj  

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Exploring Requirements Engineering for Machine Learning via a Product Case Study

Proceedings of the International Florida Artificial Intelligence Research Society Conference
Requirements Engineering (RE) is a well-defined process in software development. Through customer requirement elicitation techniques, Non-Functional Requirements (NFRs) and the Functional Requirements (FRs) that implement them, are defined.
Lynn Vonderhaar, Timothy Elvira, Juan Couder, Omar Ochoa   +3 more
doaj   +1 more source

A PSYCHOLINGUISTIC ANALYSIS OF DYSLEXIA IN BACKWARDS: THE RIDDLE OF DYSLEXIA [PDF]

, 2012
This study is under a psycholinguistic umbrella. The aim of this study is to analyze linguistic phenomena of dyslexia suffered by Brian, the main character in Backwards: The Riddle of Dyslexia.
Haira , Rizka
core  

Thirty Meter Telescope Site Testing I: Overview [PDF]

, 2009
As part of the conceptual and preliminary design processes of the Thirty Meter Telescope (TMT), the TMT site testing team has spent the last five years measuring the atmospheric properties of five candidate mountains in North and South America with an ...
Blum, R., Bustos, E., Chanan, G., Djorgovski, S. G., Els, S., Gillett, P., Gregory, B., Nelson, J., Otarola, A., Riddle, R., Schoeck, M., Seguel, J., Skidmore, W., Travouillon, T., Vasquez, J., Walker, A., Walker, D., Wang, L.   +17 more
core   +2 more sources

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Biosynthesis of Kaitocephalin: A Neuroprotective Natural Product Featuring a Peptide‐Like yet Nonpeptidic Scaffold

Angewandte Chemie, EarlyView.
Kaitocephalin (KCP) is a neuroprotective fungal metabolite with a unique scaffold of amino acids linked via C–C bonds. Genome‐transcriptome analyses identified its biosynthetic gene cluster (kpb cluster) in Eupenicillium shearii. LC‐MS/MS profiling identified four new KCP‐related compounds.
Yukari Maeno, Taro Shiraishi, Naoya Saito, Jun‐ichi Maruyama, Kazuo Shin‐ya, Tomohisa Kuzuyama   +5 more
wiley   +2 more sources

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source