Results 111 to 120 of about 86,105 (313)

Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes [PDF]

, 2018
Rifampin is a pleiotropic inducer of multiple drug metabolizing enzymes and transporters. This work utilized a global approach to evaluate rifampin effects on conjugating enzyme gene expression with relevance to human xeno- and endo-biotic metabolism ...
Desta, Zeruesenay, Eadon, Michael T., Gao, Hongyu, Gufford, Brandon T., Lin, Hai, Liu, Yunlong, Robarge, Jason D., Skaar, Todd C.   +7 more
core   +1 more source

The Microbiome in Hidradenitis Suppurativa Tunnels: A Systematic Review

International Journal of Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory disease that affects the pilosebaceous units, particularly in large skin folds. The pathophysiology of HS is multifactorial, with evidence suggesting that the microbiome plays a crucial role in perpetuating inflammation.
Alberto Soto‐Moreno, Sofía Haselgruber‐de Francisco, Javier León‐Pérez, Carmen García‐Moronta, Carlos Cuenca Barrales, Salvador Arias‐Santiago, Alejandro Molina Leyva   +6 more
wiley   +1 more source

Is Rifampin (Rifampicin) Essential for the Treatment of Rhodococcus equi Infections in Foals? A Critical Review of the Role of Rifampin

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Rifampin is an enigma among antimicrobials. Blood and tissue compartment concentrations are a “moving target” along the treatment course due to the complex pharmacodynamic interactions within the body. Rifampin concomitant therapies are for the prevention and treatment of Rhodococcus equi infection in foals, for nearly 40 years.
Keith Edward Baptiste, Niels Christian Kyvsgaard, Mohamed Omar Ahmed, Peter Damborg, Patricia M. Dowling   +4 more
wiley   +1 more source

Influence of Single Nucleotide Polymorphisms on Rifampin Pharmacokinetics in Tuberculosis Patients

Antibiotics, 2020
Rifampin (RF) is metabolized in the liver into an active metabolite 25-desacetylrifampin and excreted almost equally via biliary and renal routes. Various influx and efflux transporters influence RF disposition during hepatic uptake and biliary excretion.
Levin Thomas, Sonal Sekhar Miraj, Mallayasamy Surulivelrajan, Muralidhar Varma, Chidananda S. V. Sanju, Mahadev Rao   +5 more
doaj   +1 more source

Prevalence of Post‐Operative Infections Related to Third Molar Surgery at an Australian University Teaching Clinic: A 5‐Year Retrospective Study

Oral Surgery, EarlyView.
ABSTRACT Aim To assess the prevalence of post‐operative infection related to surgical third molar extractions at a university teaching hospital. The secondary outcome was to investigate risk factors relating to post‐operative infections, including the use of prophylactic antibiotics.
Joshal Mehta, Riddhika Ram, Peter Reher
wiley   +1 more source

Proteomes of Lactobacillus delbrueckii subsp. bulgaricus LBB.B5 Incubated in Milk at Optimal and Low Temperatures. [PDF]

, 2017
We identified the proteins synthesized by Lactobacillus delbrueckii subsp. bulgaricus strain LBB.B5 in laboratory culture medium (MRS) at 37°C and milk at 37 and 4°C.
Angel Angelov, Brett S. Phinney, Korneel Rabaey, Maria L. Marco, Michelle R. Salemi, Velitchka Gotcheva, Xiaochen Yin   +6 more
core   +2 more sources

Effect of Rifampin on the Single-Dose Pharmacokinetics of Oral Cabotegravir in Healthy Subjects

Antimicrobial Agents and Chemotherapy, 2017
Drug-drug interactions between antiretroviral medications and rifampin complicate the treatment of HIV and tuberculosis coinfection. This study evaluated the effect of rifampin on the pharmacokinetics of oral cabotegravir, an integrase strand transfer ...
S. Ford, K. Sutton, Y. Lou, Z. Zhang, A. Tenorio, C. Trezza, P. Patel, W. Spreen   +7 more
semanticscholar   +1 more source

The receptor‐like protein RXEG1 confers broad‐spectrum resistance in soybean and cotton by recognizing microbial glycoside hydrolase 12 proteins

Plant Biotechnology Journal, EarlyView.
Summary Plants diseases cause substantial crop yield loss and threaten food security. Enhancing plant genetic resistance is a major strategy to mitigate the impact of plant diseases on agricultural production. The leucine‐rich repeat receptor‐like protein RXEG1 recognizes the glycoside hydrolase 12 (GH12) protein XEG1 secreted by Phytophthora sojae to ...
Mengzhu Zeng, Ping Qiu, Haibing Ouyang, Yujing Sun, Zhiyuan Chen, Yuanyuan Cheng, Mingmei Zhang, Yu Ye, Lei Wang, Zuling Zheng, Hao Wang, Tianyao Liu, Wei Zhao, Kaixuan Duan, Yan Wang, Longfu Zhu, Yuanchao Wang   +16 more
wiley   +1 more source

Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. [PDF]

, 2019
Introduction:Treatment of open fractures routinely involves multiple surgeries and delayed definitive fracture fixation because of concern for infection.
Bernthal, NM, Hegde, V, Loftin, AH, Niska, J, Segura, T, Stavrakis, AI, Weixian, X, Zhu, S   +7 more
core  

Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)

Veterinary Dermatology, EarlyView.
Abstract Background Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler, Christine L. Cain, Lluís Ferrer, Koji Nishifuji, Katarina Varjonen, Mark G. Papich, Luca Guardabassi, Siân M. Frosini, Emi N. Barker, Scott J. Weese   +9 more
wiley   +1 more source