Results 91 to 100 of about 48,908 (228)
Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri +10 more
wiley +1 more source
Warfarin-Rifampin Drug Interaction in a Pediatric Patient
Rifampin has been documented to significantly attenuate the effect of warfarin in adult patients. No data have been presented on the use of rifampin and warfarin in a pediatric patient.
Donald L. Yee +2 more
core +1 more source
Nanoshell Fabrication Techniques for Probiotic Encapsulation: A Comprehensive Review
ABSTRACT Probiotics, beneficial microorganisms, confer numerous health benefits when administered. However, their efficacy is hindered by harsh gut conditions, including acidity, bile acids, and enzymatic degradation. To overcome these challenges, encapsulation and nanoshell technology have emerged as a pivotal strategy to enhance probiotic stability ...
Tuba Mustafa +12 more
wiley +1 more source
Introducción. La tuberculosis es un problema de salud pública a nivel mundial. En 2014, la Organización Mundial de la Salud estimó que se habían presentado 9,6 millones de casos nuevos y 480.000 multirresistentes.
Claudia Llerena +3 more
doaj +1 more source
The use of rifampin as an adjunct in biofilm-associated infections is based on the ability to penetrate into biofilms and a presumed activity against dormant bacteria.
Stobberingh, Ellen E. +9 more
core +1 more source
Successful Anticoagulation With Warfarin After Switching From Rifampin to Rifabutin
Purpose: A case of a patient receiving warfarin for pulmonary embolism (PE) concomitantly with rifampin for treatment of active pulmonary tuberculosis (PTB) is presented.
Samantha L. Landolfa +3 more
core +1 more source
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease characterised by painful nodules, abscesses, and draining and non‐draining tunnels. Currently, there are two biologics approved in Canada for the treatment of moderate‐to‐severe HS, adalimumab (anti‐TNF) and secukinumab (anti‐IL‐17A).
Irina Turchin +4 more
wiley +1 more source
ABSTRACT Background and Aims Pruritus is a debilitating, under‐prioritized symptom of primary biliary cholangitis (PBC). This study assessed its impact on healthcare resource utilization (HCRU) and costs in the US. Methods A retrospective cohort study of individuals with PBC was conducted using Komodo's claims and laboratory data between September 1 ...
Robert G. Gish +8 more
wiley +1 more source
Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae [PDF]
The rpoB gene encodes the β subunit of RNA polymerase holoenzyme in Mycobacterium leprae (M. leprae). Missense mutations in the rpoB gene were identified as etiological factors for rifampin resistance in leprosy.
Ascher, DB +23 more
core +1 more source
Salmonella enterica serovar Gallinarum–Pullorum isolated from chickens reveals a critical 89.13% prevalence of multidrug resistance. High phenotypic resistance to amoxicillin and tetracycline is genetically underpinned by a robust presence of resistance‐conferring genes (notably tetA, sul1, and blaCMY), highlighting a significant zoonotic threat to ...
Md. Masuk Rahman Kingshuk +3 more
wiley +1 more source

