Results 81 to 90 of about 49,037 (222)

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

Veterinary Dermatology, EarlyView.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro, Emma R. Bollig, Jennifer L. Granick   +2 more
wiley   +1 more source

Combination of Oral Doxycycline and Rifampin for Pan‐Drug Resistant Klebsiella pneumoniae Infection: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari, Sepideh Elyasi, Farshad Abedi   +2 more
wiley   +1 more source

Occurrence of Antimicrobial Resistance in Kocuria rhizophila Bacteria Isolated From Salmo munzuricus (Teleostei: Salmonidae) Samples in Natural Resources

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study examined the antibiotic susceptibility of Kocuria rhizophila isolated from Salmo munzuricus samples taken from the Munzur River. The isolates are resistant to Penicillin G, moderately susceptible to gentamicin and tetracycline, and highly susceptible to amoxicillin and ampicillin.
Bülent KAR
wiley   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

Multiplex detection of mutations in clinical isolates of rifampin-resistant Mycobacterium tuberculosis by short oligonucleotide Ligation assay on DNA chips [PDF]

, 2004
A new approach, short-oligonucleotide-ligation assay on DNA chip (SOLAC), is developed to detect mutations in rifampin-resistant Mycobacterium tuberculosis. The method needs only four common probes to detect 15 mutational variants of the rpoB gene within
Qiang Liu, Xian-En Zhang, Ya-Feng Zhou, Wei-Hong Xie and Zhi-Jun Fu, Zhang, XE, Chinese Acad Sci, Wuhan Inst Virol, Wuhan 430071, Peoples R China, Zhi-Ping Zhang, Hong-Bing Lu, Jiao-Yu Deng   +7 more
core  

New combination for patients with latent tuberculosis infection: A pilot study

Journal of Medical Sciences, 2018
Background: Latent tuberculosis infection (LTBI) is characterized by the presence of immune responses to Mycobacterium tuberculosis without clinical evidence of active TB.
Te-Yu Lin, Feng-Cheng Liu
doaj   +1 more source

Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak, Rachael Moorin, Jeff Hughes, Karl Gruber, David Youens   +4 more
wiley   +1 more source

Mean Rifapentine and Rifampin Serum Concentrations versus Time [PDF]

, 2013
Mice were administered a single dose of 7.5, 10, 15, and 20 mg/kg of rifapentine or 10 mg/kg of rifampin. P, rifapentine; R, rifampin.
Kathy N Williams (37571), Ming Zhang (9736), Sandeep Tyagi (37573), Charles A Peloquin (37572), Andrew A Vernon (37574), Ian M Rosenthal (37570), William R Bishai (37575), Richard E Chaisson (37576), Jacques H Grosset (37577), Eric L Nuermberger (37578)   +9 more
core   +1 more source

The Study of the Protective Effect of Black Cumin (Nigella sativa linn.)Ethanolic Extract Against Rifampin-induced Hepatotoxicity in Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives:Anti-tuberculosis drug, rifampin, is toxic for liver. This study was conducted to determine the preventive effects of black cumin (Nigella sativaLinn.) extract against rifampin-induced hepatotoxicity in rats. Methods: In this
Mehrdad Neshat Gharamaleki, Daryoush Mohajeri   +1 more
doaj  

A Physiologically Based Pharmacokinetic Model to Predict Potential Drug–Drug Interactions of TPN171, a Novel Phosphodiesterase Type 5 Inhibitor

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT TPN171 is a potent phosphodiesterase type 5 inhibitor used to treat pulmonary arterial hypertension and erectile dysfunction, primarily metabolized by CYP3A4. This study aimed to evaluate its drug–drug interaction (DDI) potential and determine the optimal dosing when co‐administered with CYP3A4 modulators.
Guanghui Tian, Tao Chen, Lei Li, Zhiqiang Wang, Hao Yang, Jiaxiang Juan, Yuanqin Duan, Jianghong Pei, Jingying Jia   +8 more
wiley   +1 more source