Results 81 to 90 of about 51,024 (230)

Adequacy of rifampin absorption after jejunostomy tube administration [PDF]

, 2016
It is not always possible to administer antituberculosis pharmacotherapy orally for reasons that may be a direct consequence of tuberculosis itself. To our knowledge, no published literature is available regarding antituberculosis drug absorption via ...
Mike B.J. Beadsworth, Saye H. Khoo, Beadsworth, MBJ, Singh, B, Bhagteshwar Singh, Katharine E. Stott, Stott, KE, Vaudrey, K, Davies, G, Geraint Davies, Khoo, SH, Kate Vaudrey   +11 more
core   +1 more source

New combination for patients with latent tuberculosis infection: A pilot study

Journal of Medical Sciences, 2018
Background: Latent tuberculosis infection (LTBI) is characterized by the presence of immune responses to Mycobacterium tuberculosis without clinical evidence of active TB.
Te-Yu Lin, Feng-Cheng Liu
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes

, 2013
Rifampin causes drug interactions by altering hepatic drug metabolism. Because microRNAs (miRNAs) have been shown to regulate genes involved in drug metabolism, we determined the effect of rifampin on the expression of hepatic miRNAs.
Philips, Santosh, Lin, Hai, Liu, Yunlong, Goswami, Chirayu, Ramamoorthy, Anuradha, Flockhart, David A., Skaar, Todd C., Li, Lang, Desta, Zeruesenay, Gaedigk, Andrea   +9 more
core   +1 more source

Enhanced Biofilm Disruption in Methicillin-Resistant Staphylococcus aureus Using Rifampin and Fluoroquinolone Combinations

Pathogens
Staphylococcus aureus biofilms complicate the treatment of device-related infections. We hypothesized that combining rifampin with fluoroquinolones could eradicate biofilms even in antimicrobial-resistant S. aureus strains.
Yu Ri Kang, Joo-Young Park, Doo Ryeon Chung, Minhee Kang, Jae-Hoon Ko, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Kyong Ran Peck   +8 more
doaj   +1 more source

Tuberculosis Misdiagnosed as Bronchogenic Carcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The patient, a 77‐year‐old male smoker, presented to the Emergency Department with dyspnea, cough, fever, night sweats, and 12 kg weight loss, initially suggesting COPD or lung cancer. Chest CT revealed a right upper lobe mass, pleural effusion, and lymphadenopathy, prompting suspicion of malignancy.
Pejman Hosseinzadeh, Sara Samadi, Shirin Taraz Jamshidi, Sayed Mortaza Fayez, Mahnaz Mozdourian   +4 more
wiley   +1 more source

Efficacy of antibiotic treatment of implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study

Drug Design, Development and Therapy, 2017
Felix Greimel,1 Christine Scheuerer,1 Andre Gessner,2 Michaela Simon,2 Thomas Kalteis,1 Joachim Grifka,1 Achim Benditz,1 Hans-Robert Springorum,1 Jens Schaumburger1 1Department of Orthopedics, University Medical Center Regensburg, Asklepios ...
Greimel F, Scheuerer C, Gessner A, Simon M, Kalteis T, Grifka J, Benditz A, Springorum HR, Schaumburger J   +8 more
doaj  

Synergism of Linezolid and Rifampin to Combat Multidrug-Resistant Environmental Enterococci Isolates

پیاورد سلامت, 2022
Background and Aim: Wastewater is one of the most dangerous and important sources of pathogens and their treatment does not always guarantee the elimination of pathogenic bacteria.
Mobina Noori, Leila Fozouni, Ania Ahani Azari   +2 more
doaj  

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Fluoroquinolones and rifampin combination in the backdrop of heteroresistant tuberculosis [PDF]

The impact of heteroresistance on tuberculosis (TB) treatment outcomes is unclear, as is the role of different rifampin and isoniazid exposures on developing resistance mutations.
Akkerman, Onno W; id_orcid, Singh, Sanjay, Boorgula, Gunavanthi D, Gumbo, Tawanda, Sturkenboom, Marieke G G; id_orcid, Thomas, Tania A, Engelthaler, David M, Vogensen, Vanessa B; id_orcid, Allende, Christopher J, Srivastava, Shashikant   +9 more
core   +1 more source