Results 21 to 30 of about 4,133,743 (170)

Outcomes of community-based differentiated models of multi-month dispensing of antiretroviral medication among stable HIV-infected patients in Lesotho: a cluster randomised non-inferiority trial protocol

BMC Public Health, 2018
Background Current World Health Organization (WHO) guidelines recommend early initiation of HIV positive patients on antiretroviral therapy (ART) irrespective of their clinical or immunological status known as the test and start approach.
I. O. Faturiyele, T. Appolinare, N. Ngorima-Mabhena, G. Fatti, I. Tshabalala, V. J. Tukei, P. T. Pisa   +6 more
doaj   +1 more source

¿Vecinas, policías o expertas? Las fuentes informativas en las noticias sobre feminicidios

Quaderns de Filologia: Estudis Lingüístics, 2021
El adecuado uso de las fuentes informativas se ha identificado tradicionalmente como uno de los elementos más relevantes a la hora de informar sobre los asesinatos machistas.
Ainhoa Novo Arbona, Simón Peña Fernández, Leyre Eguskiza Sesumaga, Eva Jiménez Martín, Lucía Martínez Odriozola   +4 more
doaj   +1 more source

Breast abnormalities in adolescents receiving antiretroviral therapy

Southern African Journal of HIV Medicine, 2019
Background: Antiretrovirals, particularly efavirenz (EFV), have been shown to cause breast abnormalities in adults. Little is known about the prevalence of these adverse effects among adolescents receiving antiretroviral therapy (ART).
Jackie L. Dunlop, Wiedaad Slemming, Kathryn Schnippel, Caroline Makura, Leon J. Levin, Sarah Rayne, Marnie Vujovic, Cynthia Firnhaber   +7 more
doaj   +1 more source

Treatment outcomes and costs of a simplified antiretroviral treatment strategy for hepatitis C among Hepatitis C Virus and Human Immuno deficiency Virus co‐infected patients in Ukraine

JGH Open, 2022
Background and Aim To demonstrate the use of a standard dose of ledipasvir (LDV) and sofosbuvir (SOF), with or without ribavirin, to treat hepatitis C and hepatitis C/HIV co‐infection in Ukraine.
Sergie Antoniak, Charles S Chasela, Morgan Julie Freiman, Yulia Stopolianska, Tetiana Barnard, Malini M Gandhi, Maria Liulchuk, Zhanna Tsenilova, Tretiakov Viktor, Jeri Dible, Constance Wose Kinge, Francis Akpan, Thomas Minior, Ntombi Sigwebela, Sofiane Mohamed, Matthiue Barralon, Fadzai Marange, Clint Cavenaugh, Charles Vander Horst, Svitlana Antonyak, Thembisile Xulu, Kara W Chew, Ian Sanne, Sydney Rosen, for EQUIP Health   +24 more
doaj   +1 more source

La institucionalización del paisaje de las Rías Baixas

Cuadernos de Geografía de la Universitat de València, 2022
Este artículo aborda el estudio del paisaje desde diferentes perspectivas. En primer lugar, el paisaje como teoría, analizada desde un punto de vista holístico.
Rubén C. Lois González, Breixo Martins Rodal   +1 more
doaj   +1 more source

Characterization of the aryl hydrocarbon receptor as a potential candidate to improve cancer T cell therapies

Cancer Immunology, Immunotherapy
The efficacy of T-cell-based cancer therapies can be limited by the tumor microenvironment which can lead to T cell dysfunction. Multiple studies, particularly in murine models, have demonstrated the capacity of the aryl hydrocarbon receptor (AHR) to ...
Valentine De Castro, Oumaïma Abdellaoui, Barbara Dehecq, Babacar Ndao, Patricia Mercier-Letondal, Alexandra Dauvé, Francine Garnache-Ottou, Olivier Adotévi, Romain Loyon, Yann Godet   +9 more
doaj   +1 more source

GABARAPL1 is important for the activation of HRI during eIF2α phosphorylation-dependent stress response to sodium arsenite

Scientific Reports
Sodium arsenite is known to activate the integrated stress response pathway, through the activation of the heme-regulated inhibitor kinase (HRI). Upon activation, HRI phosphorylates the α subunit of the translation initiation factor eIF2, resulting in ...
Sarah Campenet, Mathis Lamarre, Jules Durand, Valérie Perez, Paul Peixoto, Régis Delage-Mourroux, Michaël Guittaut, Aurélie Baguet, Gilles Despouy   +8 more
doaj   +1 more source

Potential Carbon Savings with Day-case Compared to Inpatient Transurethral Resection of Bladder Tumour Surgery in England: A Retrospective Observational Study Using Administrative Data

European Urology Open Science, 2023
Background: The National Health Service (NHS) in England has set a net-zero target for carbon emissions by 2040. Increasing use of day-case surgery pathways may help in meeting this target.
Manraj Phull, Hasina Begum, Joseph B. John, Maria van Hove, John McGrath, Kieran O'Flynn, Tim W.R. Briggs, William K. Gray   +7 more
doaj   +1 more source

The Role of Etymological Knowledge in the Philosophical Approach to the Word “Ḥaqq” (Truth, Right, Reality etc.) in the Holy Quran [PDF]

آموزه‌‌های فلسفه اسلامي, 2020
The word ḥaqq (truth, right, reality etc.) is one of the most widely used words in the Holy Quran, which despite its external clarity, its exact meaning requires etymology, and in the Holy Quran, it has been used in more than 30 different meanings ...
Bibi Zainab Hosseini, Hossein Ghaemi Asl, Ruqayyah Badsār   +2 more
doaj   +1 more source

Insulin restores renal neprilysin (NEP) and attenuates the shedding of urinary NEP and KIM-1 in diabetic Akita mice

Frontiers in Pharmacology
ObjectiveDiabetic kidney disease (DKD) is characterized by dysregulation of the renin-angiotensin system (RAS) and renal tubular injury. We investigated whether insulin treatment preserves renal homeostasis by modulating neprilysin (NEP), arginase-2 (Arg-
Rupinder K. Gill, Esam S. B. Salem, Nadja Grobe, Khalid M. Elased   +3 more
doaj   +1 more source