Results 101 to 110 of about 1,765,259 (347)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Dysthanasia: Between the Life Extension And the Right to Die With Dignity
Revista Brasileira de Direitos e Garantias Fundamentais, 2016 During the XX century, arise new techniques and drugs that can prolong life. However, an unreasonable extension of the vital process of human being that does not have dignified conditions of living it could result in a slow and painful death. Dysthanasia
Alice Pompeu Viana +1 more
doaj +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
End of Life Care: The Importance of Culture and Ethnicity [PDF]
, 2010 Despite Australia's cultural diversity, there is little doubt that ethnic minority groups continue to have less access to health care systems, let alone culturally appropriate care, including palliative and end of life care.
Jane Phillips
core
A licitude civil da prática da ortotanásia por médico em respeito à vontade livre do paciente
Revista BioéticaPor meio de interpretação constitucional baseada no princípio fundamental da dignidade da pessoa humana e no direito à vida, entende-se que a Constituição Federal protege o direito à morte digna, enquanto inexiste norma federal que disponha sobre o tema.
Maria Luiza Monteiro da Cruz +1 more
doaj
On the left, a superb wetting agent. On die right, a tremendously effective defoamer. [PDF]
, 1987 openalex +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Economic interests and the origins of electoral systems [PDF]
Die gängige Begründung – basierend auf der bahnbrechenden Arbeit Rokkans – dafür, dass ein spezifisches Wahlsystem bevorzugt wird, ist, dass die Verhältniswahl („proportional respresentation“ oder „PR“) von einer zersplitterten Rechte eingeführt wurde ...
Cusack, Thomas R. +2 more
core
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source