Results 51 to 60 of about 1,765,259 (347)
Older Lesbians, Gay Men and the ‘Right to Die’ debate - ‘I always keep a lethal dose of something, because I don’t want to become an elderly isolated person.' [PDF]
, 2017 This article considers the ‘right to die’ debate from the perspectives of older lesbians and gay men, drawing upon data gathered for a PhD in law. My argument is that older lesbians and gay men are multiply disadvantaged (a) by an increased risk of ...
Westwood, SL
core +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Kants Weltbürgerrecht Revisited Eine Replik
Revista de Estudios Kantianos, 2023 The article is a response to the commentaries on „Migration und Weltbürgerrecht“ (2019) by Gustavo Leyva, Daniel Loewe and Roberta Picardi. After a brief introduction, I highlight the central questions of the commentaries and formulate answers to the ...
Karoline Reinhardt
doaj +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
The fight-to-die: older people and death activism
International Journal of Ageing and Later Life, 2012 This article explores the activities and convictions of older right-to-die activists who belong to a small but very active interest group based in Scotland, UK, called Friends at the End (FATE).
Naomi Richards
doaj +1 more source
BMC Medical Ethics, 2020 It has historically been a crime in Canada to provide assistance to someone in ending their own life, however, this paradigm was inverted in 2015 when the Supreme Court of Canada (SCC) ruled that restrictions on this practice, within certain defined ...
Travis Carpenter, Lucas Vivas
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Getting through the Door: Threshold Procedural Considerations in Right-to-Die Litigation [PDF]
, 1995 Ms. DiPaolo explains how judges may use mootness, ripeness and standing to avoid getting involved in right-to-die cases.
DiPaolo, Sharon F.
core +1 more source