Results 61 to 70 of about 92,832,169 (281)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
It has historically been a crime in Canada to provide assistance to someone in ending their own life, however, this paradigm was inverted in 2015 when the Supreme Court of Canada (SCC) ruled that restrictions on this practice, within certain defined ...
Travis Carpenter, Lucas Vivas
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The adaptation of the therapeutic effort: science, technology and society
The scientific and technological development has an impact in all the spheres of society. The adaptation of the therapeutic effort is example of this. The author’s motive to carry out this bibliographic review article laid on the technological abuse as a
Gilberto de Jesús Betancourt-Betancourt +2 more
doaj
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The existence and extent of a right to die was recently examined by the Court of Appeal in the case of Re J (a Minor). The case adds to the judicial guidance available when decisions have to be taken regarding treatment of severely disabled patients or ...
McAdams, Alison L.
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Newsletter published from The National Right to Work Committee describing right to work laws enacted in Nebraska. The Committee's program to extend rights nationwide is mentioned, as well as the Sands vs. Queen City Packing Company court case.
National Right to Work Committee (U.S.)
core
Legal Problems of qualification of euthanasia in Kazakhstan
The article deals with the problem of the legal qualification of euthanasia in Kazakhstan, as well as proposals to allocate an independent structure less dangerous kind of murder.
Kopbayev D.Z., Tleuov T.M.
doaj
Diretivas antecipadas de vontade: percurso histórico na América Latina
Resumo As diretivas antecipadas de vontade são instrumento para garantir ao paciente o direito de decidir sobre seus cuidados de saúde, especialmente os relacionados ao fim da vida.
Renata da Silva Fontes Monteiro +1 more
doaj +1 more source

