Results 71 to 80 of about 2,978,181 (300)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The human right to food as a U.S. nutrition concern, 1976-2006: [PDF]

open access: yes
"For 30 years, U.S. food and nutrition scientists and policymakers concerned with food and nutrition have explored the possibility of making the human right to food (HRF) the moral and legal cornerstone of U.S.
Cohen, Marc J., Messer, Ellen
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Conflict, food insecurity, and globalization: [PDF]

open access: yes
"We explore how globalization, broadly conceived to include international humanrights norms, humanitarianism, and alternative trade, might influence peaceful and foodsecure outlooks and outcomes.
Cohen, Marc J., Messer, Ellen
core   +3 more sources

Food sovereignty in the comparative law [PDF]

open access: yesStrani pravni život, 2020
Food sovereignty is a specific concept that is, at the same time, an overarching right, an alternative model of development and a political framework, which objective is realization of the rights of local food producers and rural people to determine ...
Dokmanović Mirjana S.
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Enforcing the Right to Food in India: Bottlenecks in Delivering the Expected Outcome [PDF]

open access: yes
right to food, food security, poverty, public distribution system, targeting, corruption, accountability ...
Cheriyan, George
core  

Renewal through Participation in Global Food Security Governance: Implementing the International Food Security and Nutrition Civil Society Mechanism to the Committee on World Food Security [PDF]

open access: yes, 2012
The food commodity price rises from 2006 to 2008 engendered a period of political renewal and reform in the governance of global food security. The Committee on World Food Security (CFS) was designated as the main international forum dealing with food ...
Barling, D., Duncan, J.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Perceptions of the Right to Food Among Adults Aged 60 Years and Older. [PDF]

open access: yesEcol Food Nutr, 2023
Brady PJ   +6 more
europepmc   +1 more source

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