Results 151 to 160 of about 8,230,084 (364)

WRC Assessment re PT Mulia Knitting (Indonesia): Findings, Recommendations, and Status Report [PDF]

open access: yes, 2008
WRC report on its assessment of labor codes violations at a PT Mulia factory in Indonesia, with recommendations for remedial action.
Worker Rights Consortium
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Worker Rights Consortium Assessment re Chong Won Fashion, Inc. (The Philippines): Report of Findings and Recommendations [PDF]

open access: yes, 2007
WRC report on assessment of ongoing labor violations in the Chong Won factory in the Philippines. Connects abuses to the larger issue of political violence in the country, which blocks efforts to protect worker ...
Worker Rights Consortium
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Worker Rights Consortium Assessment re Empresas T&M (Dominican Republic): Findings, Recommendations, and Status Report [PDF]

open access: yes, 2007
WRC report on its assessment of labor violations found at the Empresas T&M factory in the Dominican Republic. Includes a description of actions taken by the company to ameliorate the issue before it closed down in ...
Worker Rights Consortium
core   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Worker Rights Consortium Assessment re Darong Printing and Embroidery (Cambodia): Findings, Recommendations, and Status Report [PDF]

open access: yes, 2009
WRC report on assessment of health and safety hazards at the Darong Printing and Embroidery factory in Cambodia.
Worker Rights Consortium
core   +1 more source

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