Results 51 to 60 of about 2,531,746 (315)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

“What is there left after losing oneself?”: 100 testimonies of genocidal torture from Gaza

open access: yesTorture
Introduction: Since 7 October 2023, the number of Palestinians detained by Israeli authorities has increased dramatically. Methods: Semi-structured in-depth interviews were conducted between December 2023 and November 2024 with 100 Palestinians who ...
Maha Aon   +7 more
doaj   +1 more source

Rights and liabilities for people with service animals

open access: yes, 2003
Title from web page (viewed Nov. 24, 2004).; "Reviewed in 2003."; Harvested from the web on 11/24/04Ohio Legal Rights Service (OLRS) publication, Rights and Liabilities for People with Service ...
Ohio Legal Rights Service.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Children's rights the rights of children and their families who need or are receiving community services.

open access: yes, 2006
Title from cover (i.e. p. [1]) of PDF document (viewed July 28, 2006).; "This publication was produced by Ohio Legal Rights Service through a contract with National Alliance on Mental Illness (NAMI) Ohio and with funding from the Ohio Department of ...
Ohio Legal Rights Service.
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Rights and the complaint process for people receiving mental health services

open access: yes, 2003
Title from web page (viewed Nov. 29, 2004).; "Reviewed in 2003."; Harvested from the web on 11/30/04Ohio Legal Rights Service (OLRS) publication, Rights and the Complaint Process for People Receiving Mental Health ...
Ohio Legal Rights Service.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Ohio DDP and funding for individual options waiver

open access: yes, 2006
Title from PDF cover (viewed on Jan. 22, 2007).; "September 2006"--P. 3 of cover.; Harvested from the web on 1/22/07Frequently asked questions about the Individual Options Waiver of the Ohio Developmental Disabilities Profile (ODDP) answered by the Ohio ...
Ohio Legal Rights Service.
core  

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