Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Should politicians be prosecute for statements made in the exercise of their mandate?
http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-en.asp?fileid=25279&lang=en http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-FR.asp?fileid=25279&lang ...
Boris Cilevičs, Committee on Legal Affairs and Human Rights
doaj
Worker Rights Consortium Assessment re Unique Garments, Swaziland: Findings and Recommendations [PDF]
WRC report on its assessment of labor code compliance at a Unique Garments factory in Swaziland.
Worker Rights Consortium
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
CHILDREN’S SOCIO-ECONOMIC RIGHTS, DEMOCRACY AND THE COURTS, 2011
Resenha de livro.
Judith Fitzpatrick, Harvard Health and Human Rights, Estados Unidos
doaj
Factory Assessment Update [PDF]
Update on WRC’s monitoring program of violations of labor standards at factories around the globe through compliance assessment and evaluation of ...
Worker Rights Consortium
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Worker Rights Consortium Assessment re PT Panarub (Indonesia): Summary of findings and Recommendations [PDF]
WRC report on its assessment of conditions at a PT Panarub factory in Indonesia. Includes findings, recommendations, and a description PT Panarub management’s response to the recommendations. Provides information concerning the factory’s follow through
Worker Rights Consortium
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Worker Rights Consortium Assessment re Gildan Activewear El Progreso (Honduras): Findings, Recommendations, and Status Report [PDF]
WRC report on its assessment of labor violations following the closure of the El Progreso factory in Honduras. Includes recommendations to remediate the problems and a description of the company’s response to the WRC ...
Worker Rights Consortium
core +1 more source

