Results 61 to 70 of about 3,268,362 (310)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The Right to Have Rights as the Right to Asylum [PDF]

open access: yesNetherlands Journal of Legal Philosophy, 2014
The Right to Have Rights as the Right to Asylum This article argues that the right to have rights, as launched by Hannah Arendt, is relative to refugee displacement and hence translates as a right to asylum. It takes issue with the dominant view that the public/private divide is the locus classicus of the meaning of this primordial right.
openaire   +1 more source

Twin Valley Behavioral Healthcare-- Columbus Campus survey results comparison between 2000 and 2001.

open access: yes, 2002
"A publication of the Ohio Legal Rights Service (OLRS), 2002."; Graphical and text-only/printer-friendly versions provided.; Description based on: 2002; title from Home page caption (viewed on Dec.
Ohio Legal Rights Service.
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Women's Rights in Transitions to Democracy : Achieving Rights, Resisting Backlash; pre-meeting and strategy sessions report

open access: yes, 2013
Arabic version available in IDRC Digital LibraryThe Association for Women’s Rights in Development (AWID) hosted its 12th International Forum in Istanbul (2012), bringing together more than 2,200 women’s rights activists from around the world under the ...

core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The right test for the right patient at the right time

open access: yesJournal of Nuclear Cardiology, 2022
Thomas, Merrill, Thompson, Randall C.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Povrede prava zajamčenih Europskom konvencijom za zaštitu ljudskih prava i temeljnih sloboda utvrđene u području upravnog prava u Republici Hrvatskoj – izabrane presude Europskog suda za ljudska prava

open access: yesZbornik Pravnog Fakulteta Sveučilišta u Rijeci
Sustav zaštite ljudskih prava uspostavljen Europskom konvencijom za zaštitu ljudskih prava i temeljnih sloboda ostvaruje se kroz nadležnost Europskog suda za ljudska prava da ispituje pojedinačne zahtjeve u kojima se podnositelji žale na povrede ...
Zvonimir Mataga, Franka Viljac Herceg
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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