Results 31 to 40 of about 194,357 (268)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Bulletin of Symbolic LogicAbstract We give a unified overview of the study of the effects of additional set theoretic axioms on quotient structures. Our focus is on rigidity, measured in terms of existence (or rather non-existence) of suitably non-trivial automorphisms of the quotients in question. A
Ilijas Farah +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Food Science and Human WellnessHyperuricemia (HUA) is a metabolic disease characterized by high levels of uric acid (UA) in the blood and varying degrees of kidney damage. Desirable nanoliposomes should simultaneously exhibit efficient biocompatibility and effective drug delivery ...
Simin Feng +6 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Frontiers in Genetics, 2020 Autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) is a rare neurodegenerative disorder caused by biallelic mutations in the SACS gene. Once thought to be limited to Charlevoix–Saguenay region of Quebec, recent evidence has indicated that
Parham Habibzadeh +8 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
"Primum non nocere (First, do no harm)". Case report
Кардиоваскулярная терапия и профилактика, 2023 Diastolic myocardial dysfunction is the most important pathogenetic factor in heart failure and makes a significant contribution to hemodynamic disorders, which leads to a significant deterioration in the quality of life and prognosis of patients.
D. A. Nefedova +2 more
doaj +1 more source
Communications in Mathematical Physics, 2004 Using very weak criteria for what may constitute a noncommutative geometry, I show that a pseudo-Riemannian manifold can only be smoothly deformed into noncommutative geometries if certain geometric obstructions vanish. These obstructions can be expressed as a system of partial differential equations relating the metric and the Poisson structure that ...
openaire +3 more sources