Results 51 to 60 of about 663,677 (295)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Quantitative Measurement of Rigidity in Parkinson’s Disease: A Systematic Review

open access: yesSensors, 2020
Rigidity is one of the cardinal symptoms of Parkinson’s disease (PD). Present in up 89% of cases, it is typically assessed with clinical scales. However, these instruments show limitations due to their subjectivity and poor intra- and inter-rater ...
María del Rosario Ferreira-Sánchez   +2 more
doaj   +1 more source

Necessary Conditions for the Generic Global Rigidity of Frameworks on Surfaces

open access: yes, 2013
A result due in its various parts to Hendrickson, Connelly, and Jackson and Jord\'an, provides a purely combinatorial characterisation of global rigidity for generic bar-joint frameworks in $\mathbb{R}^2$.
Jackson, Bill   +2 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Propagation of Torsional Surface Waves in a Nonhomogeneous Half-Space With Circular Irregularity in Free Surface

open access: yesInternational Journal of Applied Mechanics and Engineering, 2018
The present paper studies the effect of circular regularity on propagation of torsional surface waves in an elastic non-homogeneous half-space. Both rigidity and density of the half-space are assumed to vary inversely linearly with depth.
M. Sethi, A.K. Sharma, A. Sharma
doaj   +1 more source

Surface Texture after Turning for Various Workpiece Rigidities

open access: yesMachines, 2021
In the paper, we present an analysis of the surface texture of turned parts with L/D (length/diameter) ratios of 6 and 12 and various rigidity values. The studies were carried out on samples made of S355JR steel and AISI 304 stainless steel.
Michal Dobrzynski, Karolina Mietka
doaj   +1 more source

The rigidity of infinite graphs [PDF]

open access: yes, 2013
A rigidity theory is developed for the Euclidean and non-Euclidean placements of countably infinite simple graphs in R^d with respect to the classical l^p norms, for d>1 and ...
Kitson, D., Power, S. C.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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