Results 41 to 50 of about 663,677 (295)
Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek +13 more
wiley +1 more source
Hyperuricemia (HUA) is a metabolic disease characterized by high levels of uric acid (UA) in the blood and varying degrees of kidney damage. Desirable nanoliposomes should simultaneously exhibit efficient biocompatibility and effective drug delivery ...
Simin Feng +6 more
doaj +1 more source
"Primum non nocere (First, do no harm)". Case report
Diastolic myocardial dysfunction is the most important pathogenetic factor in heart failure and makes a significant contribution to hemodynamic disorders, which leads to a significant deterioration in the quality of life and prognosis of patients.
D. A. Nefedova +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
We show that the problem of whether a finite set of regular-linear axioms defines a rigid theory is undecidable.
Mikolaj Bojanczyk +2 more
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) is a rare neurodegenerative disorder caused by biallelic mutations in the SACS gene. Once thought to be limited to Charlevoix–Saguenay region of Quebec, recent evidence has indicated that
Parham Habibzadeh +8 more
doaj +1 more source
Consider a countable group Gamma acting ergodically by measure preserving transformations on a probability space (X,mu), and let R_Gamma be the corresponding orbit equivalence relation on X.
Furman, Alex
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
In the practice of modern construction, flexible centrally and eccentrically compressed reinforced concrete elements are becoming more common. In this regard, the relevance of studying their work and the mechanism of bearing capacity exhaustion increases.
A. G. Tamrazyan
doaj +1 more source

