Results 71 to 80 of about 1,728,747 (295)

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

Advanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source

Extracellular matrix rigidity controls breast cancer metastasis via TYK2-mediated mechanotransduction

Nature Communications
Mechanical cues from the extracellular matrix (ECM) regulate various cellular processes. In breast cancer, increased tumor stiffness is associated with elevated metastasis risks and poor survival.
Zhimin Hu, Hannah E. Majeski, Aida Mestre-Farrera, Shirong Cai, Arya Lalezarzadeh, Yichi Zhang, Kei-Ichiro Arimoto, Dong-Er Zhang, Helen Piwnica-Worms, Laurent Fattet, Jing Yang   +10 more
doaj   +1 more source

Tropomodulin1 regulates the biomechanical changes in macrophages induced by matrix stiffness

Mechanobiology in Medicine
The monocyte/macrophage infiltration plays critical roles in the development of atherosclerosis. Arterial stiffness is a cholesterol-independent risk factor for cardiovascular events.
Yajun Meng, Amannisa Tuersuntuoheti, Siyu Jiang, Jiayi Xie, Zejun Yue, Dingwen Xu, Xueyu Geng, Xiang Lian, Lide Xie, Lanping Amy Sung, Xifu Wang, Jing Zhou, Weijuan Yao   +12 more
doaj   +1 more source

Discrepancies Between Micro Versus Macroscale Viscoelastic Properties in a Microplastic‐Tissue Composite Model

Advanced Engineering Materials, EarlyView.
This study explores the discrepancies between bulk mechanics and spatial mapping in a tissue‐mimetic hydrogel model. Microplastic particles create localized stiff mechanical microenvironments that are detectable by cellular‐scale nanoindentation but leave bulk properties unchanged as measured by rheology.
Ahron T. Verschleisser, Baptiste Le Roi, Omri Leshem, Joshua M. Grolman   +3 more
wiley   +1 more source

The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells

, 2009
Glioblastoma multiforme (GBM) is a malignant astrocytoma\ud of the central nervous system associated with a median\ud survival time of 15 months, even with aggressive therapy.
Ulrich, T.A., de Juan Pardo, E.M., Kumar, S.   +2 more
core   +1 more source

The role of cell-matrix adhesion and cell migration in breast tumor growth and progression

Frontiers in Cell and Developmental Biology
During breast cancer progression, there is typically increased collagen deposition resulting in elevated extracellular matrix rigidity. This results in changes to cell-matrix adhesion and cell migration, impacting processes such as the epithelial ...
Lor Huai Chong, Lor Huai Chong, Ai Kia Yip, Hui Jia Farm, Hui Jia Farm, Lamees N. Mahmoud, Yukai Zeng, Keng-Hwee Chiam   +7 more
doaj   +1 more source

Data on the mechanobiological differences in the transcriptomes of human fetal and adult dermal fibroblasts in response to extracellular matrix rigidity

Data in Brief, 2019
Fetal skin is known to proceed through the wound healing process without the formation of scar tissue but rather via regeneration. Fetal dermal fibroblasts have emerged as a significant driving force in this regenerative response due to their unique ...
Mitchell J. Leih, Marisol A. Ramirez, Rachel J. Jerrell, Aron Parekh   +3 more
doaj   +1 more source

Entropy‐Driven Design of Low‐Melting‐Point Alloys via Compositionally Complex Strategy

Advanced Engineering Materials, EarlyView.
Conventional low‐melting‐point alloys (LMPAs) are limited by a narrow compositional space and inherent property trade‐offs. This review presents an entropy‐driven design strategy that overcomes these limitations, ushering in a new class of low‐melting‐point compositionally complex alloys (LMCCAs).
Yinghui Shang, Jianxiang Zhao, Zhaoqi Chen, Hao Gong, Yinsen Yan, Junlei Tao, Yong Yang   +6 more
wiley   +1 more source

Simulation‐Based Analysis of Insert Pull‐Out in Nickel‐Polyurethane Hybrid Foams Using CT‐Derived Geometries

Advanced Engineering Materials, EarlyView.
CT‐based finite element simulations combined with in situ X‐ray computed tomography are used to analyze insert pull‐out in nickel‐coated polymer foams. Despite variations in material parameters, deformation consistently concentrates within a narrow annular region around the insert.
Yannik Bautz, Jonas Fell, Hendrik Jost, Stefan Diebels, Hans‐Georg Herrmann   +4 more
wiley   +1 more source

YAP mediates apoptosis through failed integrin adhesion reinforcement

Cell Reports
Summary: Extracellular matrix (ECM) rigidity is a major effector of cell fate decisions. Whereas cell proliferation on stiff matrices, wherein Yes-associated protein (YAP) plays a pivotal role, is well documented, activation of apoptosis in response to ...
Lidan Shi, Elisabeth Nadjar-Boger, Hamidreza Jafarinia, Aurélie Carlier, Haguy Wolfenson   +4 more
doaj   +1 more source