Results 51 to 60 of about 1,728,747 (295)
Computational Modeling of In Vitro Swelling of Mitochondria: A Biophysical Approach
Molecules, 2018 Swelling of mitochondria plays an important role in the pathogenesis of human diseases by stimulating mitochondria-mediated cell death through apoptosis, necrosis, and autophagy.
Vladimir I. Makarov +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Endogenous Wage Rigidity [PDF]
We use a random survey of Swedish human resource managers to study the reasons for wage rigidity. Our findings are as follows. First, during the exceptional recession of the 1990s only 1.1 percent of workers received a wage cut.
Agell, Jonas, Bennmarker, Helge
core +2 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015 Bilindiği gibi taşıyıcı sistemlerin yatay deprem kuvvetlerinin bulunmasında en önemli parametre, sıfır sönüm oranında elastik sınırlar içerisinde kalmak kaydı ile serbest titreşim periyotlarını ve özellikle birinci doğal titreşim periyodunu bulmaktır ...
Ahmet Polat
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Abstract 3-Rigidity and Bivariate $C_2^1$-Splines I: Whiteley's Maximality Conjecture
Discrete Analysis, 2022 3-Rigidity and Bivariate $C_2^1$-Splines I: Whiteley's Maximality Conjecture, Discrete Analysis 2022:2, 50 pp. Suppose one realizes a graph $G$ by taking its vertex set to be a set of points $x_1,\dots,x_n$ in $\mathbb R^d$ and the edge joining $x_i$ to
Katie Clinch +2 more
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Role of integrins in the development of fibrosis in the trabecular meshwork
Frontiers in Ophthalmology, 2023 Primary open angle glaucoma (POAG) is a progressive and chronic disease exhibiting many of the features of fibrosis. The extracellular matrix (ECM) in the trabecular meshwork (TM) undergoes extensive remodeling and enhanced rigidity, resembling fibrotic ...
Jennifer A. Faralli +3 more
doaj +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Targeting the Akt–EphA2 axis and cell–cell adhesion enhances anoikis sensitivity in cancer cells
Scientific ReportsRigidity sensing enables cells to respond to extracellular matrix stiffness and governs survival and apoptotic decisions. Tropomyosin 2.1 (Tpm2.1), a key actin-binding protein, is frequently downregulated in cancer.
Anat Galis Vivante +3 more
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