Results 51 to 60 of about 56,763 (260)
Computational Modeling of In Vitro Swelling of Mitochondria: A Biophysical Approach
Molecules, 2018 Swelling of mitochondria plays an important role in the pathogenesis of human diseases by stimulating mitochondria-mediated cell death through apoptosis, necrosis, and autophagy.
Vladimir I. Makarov +2 more
doaj +1 more source
Bioengineering, 2023 The importance of the ovarian extracellular environment and tissue rigidity on follicle survival and development has gained attention in recent years.
Jennifer B. Nagashima +4 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015 Bilindiği gibi taşıyıcı sistemlerin yatay deprem kuvvetlerinin bulunmasında en önemli parametre, sıfır sönüm oranında elastik sınırlar içerisinde kalmak kaydı ile serbest titreşim periyotlarını ve özellikle birinci doğal titreşim periyodunu bulmaktır ...
Ahmet Polat
doaj
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Abstract 3-Rigidity and Bivariate $C_2^1$-Splines I: Whiteley's Maximality Conjecture
Discrete Analysis, 2022 3-Rigidity and Bivariate $C_2^1$-Splines I: Whiteley's Maximality Conjecture, Discrete Analysis 2022:2, 50 pp. Suppose one realizes a graph $G$ by taking its vertex set to be a set of points $x_1,\dots,x_n$ in $\mathbb R^d$ and the edge joining $x_i$ to
Katie Clinch +2 more
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Role of integrins in the development of fibrosis in the trabecular meshwork
Frontiers in Ophthalmology, 2023 Primary open angle glaucoma (POAG) is a progressive and chronic disease exhibiting many of the features of fibrosis. The extracellular matrix (ECM) in the trabecular meshwork (TM) undergoes extensive remodeling and enhanced rigidity, resembling fibrotic ...
Jennifer A. Faralli +3 more
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Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad +22 more
wiley +1 more source
Improvement by Nanofibers of Load Transfer in Carbon Fiber Reinforced Composites
Fibers, 2015 This paper focuses on the load transfer improvement caused by nanofibers (NF) in carbon fiber reinforced composites. Load transfer is defined as the ability to transfer the mechanical loading between two adjacent fibers through the surrounding matrix. NF
Alexandre Vivet +4 more
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