Results 31 to 40 of about 1,728,747 (295)

Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis. [PDF]

open access: yesPLoS ONE, 2012
Tumor cells in vivo encounter diverse types of microenvironments both at the site of the primary tumor and at sites of distant metastases. Understanding how the various mechanical properties of these microenvironments affect the biology of tumor cells ...
Robert W Tilghman   +10 more
doaj   +1 more source

Rigidity and normal modes in random matrix spectra [PDF]

open access: yesNuclear Physics A, 1999
12 pages, 1 LaTeX ...
Andersen, A.   +2 more
openaire   +2 more sources

Kronecker Products, Low-Depth Circuits, and Matrix Rigidity [PDF]

open access: yesSIAM Journal on Computing, 2021
For a matrix $M$ and a positive integer $r$, the rank $r$ rigidity of $M$ is the smallest number of entries of $M$ which one must change to make its rank at most $r$. There are many known applications of rigidity lower bounds to a variety of areas in complexity theory, but fewer known applications of rigidity upper bounds.
openaire   +3 more sources

The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

open access: yesScientific Reports, 2018
There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer ...
Andrew J. McKenzie   +5 more
doaj   +1 more source

Rigidity of a simple extended lower triangular matrix [PDF]

open access: yesInformation Processing Letters, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Meena Mahajan, Jayalal Sarma
openaire   +3 more sources

Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion

open access: yeseLife, 2015
Cardiomyocyte (CM) maturation in mammals is accompanied by a sharp decline in their proliferative and regenerative potential shortly after birth. In this study, we explored the role of the mechanical properties of the underlying matrix in the regulation ...
Yfat Yahalom-Ronen   +4 more
doaj   +1 more source

Matrix Rigidity Depends on the Target Field.

open access: yes, 2021
The rigidity of a matrix A for target rank r is the minimum number of entries of A that need to be changed in order to obtain a matrix of rank at most r (Valiant, 1977). We study the dependence of rigidity on the target field. We consider especially two natural regimes: when one is allowed to make changes only from the field of definition of the matrix
László Babai, Bohdan Kivva
openaire   +3 more sources

A dynamic basal complex modulates mammalian sperm movement

open access: yesNature Communications, 2021
Centrioles are ancient organelles with a conserved architecture and their rigidity is thought to restrict microtubule sliding. Here authors show that, in mammalian sperm, the atypical distal centriole and its surrounding atypical pericentriolar matrix ...
Sushil Khanal   +7 more
doaj   +1 more source

Utilizing Frémy's Salt to Increase the Mechanical Rigidity of Supramolecular Peptide-Based Gel Networks

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Peptide-based supramolecular gels are an important class of biomaterials that can be used for biomedical applications ranging from drug delivery to tissue engineering.
Galit Fichman, Joel P. Schneider
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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