Results 21 to 30 of about 56,763 (260)

Altering adsorbed proteins or cellular gene expression in bone-metastatic cancer cells affects PTHrP and Gli2 without altering cell growth

Data in Brief, 2015
The contents of this data in brief are related to the article titled “Matrix Rigidity Regulates the Transition of Tumor Cells to a Bone-Destructive Phenotype through Integrin β3 and TGF-β Receptor Type II”.
Jonathan M. Page, Alyssa R. Merkel, Nazanin S. Ruppender, Ruijing Guo, Ushashi C. Dadwal, Shellese Cannonier, Sandip Basu, Scott A. Guelcher, Julie A. Sterling   +8 more
doaj   +1 more source

Matrix rigidity regulates cancer cell growth and cellular phenotype.

PLoS ONE, 2010
BackgroundThe mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent cancer cells respond to changes in the mechanical properties (rigidity/stiffness) of the ...
Robert W Tilghman, Catharine R Cowan, Justin D Mih, Yulia Koryakina, Daniel Gioeli, Jill K Slack-Davis, Brett R Blackman, Daniel J Tschumperlin, J Thomas Parsons   +8 more
doaj   +1 more source

Sharp rigidity estimates for incompatible fields as a consequence of the Bourgain Brezis div-curl result

Comptes Rendus. Mathématique, 2021
In this note we show that a sharp rigidity estimate and a sharp Korn’s inequality for matrix-valued fields whose incompatibility is a bounded measure can be obtained as a consequence of a Hodge decomposition with critical integrability due to Bourgain ...
Conti, Sergio, Garroni, Adriana
doaj   +1 more source

Linking Matrix Rigidity with EMT and Cancer Invasion [PDF]

Developmental Cell, 2020
The extracellular matrix (ECM) plays a major role in cancer progression through its increased deposition and alignment. In this issue of Developmental Cell, Fattet et al. reveal a pathway in which ECM stiffness promotes EPHA2/LYN complex activation, leading to TWIST1 nuclear localization and triggering EMT in breast cancer.
Manon, Ros, Margaux, Sala, Frédéric, Saltel   +2 more
openaire   +2 more sources

Assessment of the Impact of the Rigidity of Nodes on the Operating Reliability of EPSs [PDF]

E3S Web of Conferences, 2019
The operating reliability of electrical power systems is mostly based on the topology and parameters of the schemes considered in this article. The preliminary (before the calculation of operating conditions) analysis of the rigidity or sensitivity of ...
Chemborisova Nailya
doaj   +1 more source

Data on the effects of ECM rigidity on actomyosin contractility and invadopodia activity in individual versus pairs of head and neck squamous cell carcinoma cells

Data in Brief, 2022
Migration through the extracellular matrix (ECM) is essential for cancer cells to escape the primary tumor and invade neighboring tissues with the potential for metastasis [1].
Rachel Jerrell, Mitchell Leih, Aron Parekh   +2 more
doaj   +1 more source

Matrix rigidity-modulated cardiovascular organoid formation from embryoid bodies.

PLoS ONE, 2014
Stem cell clusters, such as embryoid bodies (EBs) derived from embryonic stem cells, are extensively studied for creation of multicellular clusters and complex functional tissues.
Artem Shkumatov, Kwanghyun Baek, Hyunjoon Kong   +2 more
doaj   +1 more source

Analysis of Mechanical Properties of Unidirectional Flax Roving and Sateen Weave Woven Fabric-Reinforced Composites

AUTEX Research Journal, 2021
Natural fiber-reinforced composites are getting more attention from researchers and manufacturing companies to replace metals and synthetic materials that have dominated the manufacturing industries.
Lemmi Tsegaye Sh., Barburski Marcin, Samuel Bethalihem T.   +2 more
doaj   +1 more source

Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers

iScience, 2023
Summary: Contractile force generated in actomyosin stress fibers (SFs) is transmitted along SFs to the extracellular matrix (ECM), which contributes to cell migration and sensing of ECM rigidity.
Hiroki Katsuta, Satoru Okuda, Kazuaki Nagayama, Hiroaki Machiyama, Satoru Kidoaki, Masashi Kato, Masahiro Sokabe, Takaki Miyata, Hiroaki Hirata   +8 more
doaj   +1 more source

Extracellular Matrix Rigidity Promotes Invadopodia Activity [PDF]

Current Biology, 2008
Invadopodia are actin-rich subcellular protrusions with associated proteases used by cancer cells to degrade extracellular matrix (ECM) [1]. Molecular components of invadopodia include branched actin-assembly proteins, membrane trafficking proteins, signaling proteins, and transmembrane proteinases [1]. Similar structures exist in nontransformed cells,
Alexander, Nelson R., Branch, Kevin M., Parekh, Aron, Clark, Emily S., Iwueke, Izuchukwu C., Guelcher, Scott A., Weaver, Alissa M.   +6 more
openaire   +2 more sources