Results 41 to 50 of about 56,763 (260)
A dynamic basal complex modulates mammalian sperm movement
Nature Communications, 2021 Centrioles are ancient organelles with a conserved architecture and their rigidity is thought to restrict microtubule sliding. Here authors show that, in mammalian sperm, the atypical distal centriole and its surrounding atypical pericentriolar matrix ...
Sushil Khanal +7 more
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Frontiers in Bioengineering and Biotechnology, 2021 Peptide-based supramolecular gels are an important class of biomaterials that can be used for biomedical applications ranging from drug delivery to tissue engineering.
Galit Fichman, Joel P. Schneider
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Matrix rigidity and the Croot-Lev-Pach lemma
Theory Comput., 2017 Matrix rigidity is a notion put forth by Valiant as a means for proving arithmetic circuit lower bounds. A matrix is rigid if it is far, in Hamming distance, from any low rank matrix. Despite decades of efforts, no explicit matrix rigid enough to carry out Valiant's plan has been found.
Zeev Dvir, Benjamin L. Edelman
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Hierarchical Orthogonal Matrix Generation and Matrix-Vector Multiplications in Rigid Body Simulations [PDF]
SIAM Journal on Scientific Computing, 2018 In this paper, we apply the hierarchical modeling technique and study some numerical linear algebra problems arising from the Brownian dynamics simulations of biomolecular systems where molecules are modeled as ensembles of rigid bodies. Given a rigid body $p$ consisting of $n$ beads, the $6 \times 3n$ transformation matrix $Z$ that maps the force on ...
Fuhui Fang +4 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Some aspects of the stic system stability calculation [PDF]
Facta Universitatis. Series: Architecture and Civil Engineering, 2009 The problem presented in this paper has been treated intensively by various researchers. However, considering that by its nature the problem of structure stability belongs to the area of nonlinear analysis, it represents an inexhaustible source for ...
Bujar Emra, Stojić Dragoslav
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Recent Progress on Matrix Rigidity -- A Survey
CoRR, 2020 The concept of matrix rigidity was introduced by Valiant(independently by Grigoriev) in the context of computing linear transformations. A matrix is rigid if it is far(in terms of Hamming distance) from any matrix of low rank. Although we know rigid matrices exist, obtaining explicit constructions of rigid matrices have remained a long-standing open ...
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source