Results 71 to 80 of about 193,480 (301)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Rigidity results on Liouville equation

Communications in Analysis and Geometry
14 ...
Eremenko, Alexandre, Gui, Changfeng, Li, Qinfeng, Xu, Lu   +3 more
openaire   +3 more sources

Rigidity and Non-existence Results for Collapsed Translators [PDF]

International Mathematics Research Notices
Abstract We prove a rigidity result for mean curvature self-translating solitons, characterizing the grim reaper cylinder as the only finite entropy self-translating 2-surface in $\mathbb{R}^{3}$ of width $\pi $ and bounded from below.
Impera, Debora, Møller, Niels Martin, Rimoldi, Michele   +2 more
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Cogwheel rigidity in Parkinson's disease: Clinical, biomechanical and neurophysiological features

Neurobiology of Disease
Objectives: Cogwheel rigidity in Parkinson's disease has been poorly investigated so far, thus leaving the scientific interpretation of this phenomenon substantially unsolved.
Marco Falletti, Francesco Asci, Alessandro Zampogna, Martina Patera, Antonio Suppa   +4 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Price Points and Price Rigidity [PDF]

We study the link between price points and price rigidity, using two datasets: weekly scanner data, and Internet data. We find that: “9” is the most frequent ending for the penny, dime, dollar and ten-dollar digits; the most common price changes are ...
Daniel Levy, Mark Bergen, Dongwon Lee, Robert J. Kauffman, Haipeng (Allan) Chen   +4 more
core   +4 more sources

Effects of the semi-rigidity coefficients on numerical analysis results in chair side frame joints

Turkish Journal of Forestry
In this study, it is aimed to determine the semi-rigidity coefficients related to joints of chair side frame and to use them numerical analyses with finite element method (FEM).
Tolga Kuşkun, Ali Kasal, Mustafa Batuhan Ulun   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source