Results 51 to 60 of about 9,558 (217)

Photophysical Exploration of Alectinib and Rilpivirine: Insights from Theory and Experiment

open access: yesMolecules, 2023
Due to the excellent characteristics of fluorescence-based imaging, such as non-invasive detection of biomarkers in vitro and in vivo with high sensitivity, good spatio-temporal resolution and fast response times, it has shown significant prospects in ...
Chun Zhang   +7 more
doaj   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Combination therapies, effectiveness, and adherence in patients with HIV infection: clinical utility of a single tablet of emtricitabine, rilpivirine, and tenofovir

open access: yesHIV/AIDS: Research and Palliative Care, 2013
Mark A WainbergMcGill University AIDS Centre, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, CanadaAbstract: A recent addition to the anti-human immunodeficiency virus armamentarium of drugs is rilpivirine, which is a potent non ...
Wainberg MA
doaj  

Real-World Experience with Long-Acting Injectable Cabotegravir/Rilpivirine in HIV Patients with Unsuppressed Viral Load

open access: yesViruses
Long-acting injectable cabotegravir/rilpivirine (CAB/RPV-LA) is currently approved as a maintenance therapy for people with HIV (PWH) who are virologically suppressed.
Marcello Trizzino   +9 more
doaj   +1 more source

Experiences to date with the logistical management of long-acting cabotegravir and rilpivirine

open access: yesDrugs in Context, 2022
The logistical management of an injectable therapy for the treatment of HIV can be expensive, time consuming, frustrating and riddled with barriers. In this Commentary, we describe our experiences to date with acquiring, storing, handling, administering ...
Kamile Johnson, Mark T Sawkin
doaj   +1 more source

Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery [PDF]

open access: yes, 2019
Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo ...
Haipeng, Yin   +3 more
core   +1 more source

PKRxiv: A Best Practice Model for Advancing Pharmacoequity Through Open Pharmacokinetic Data Sharing

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1235-1248, May 2026.
Model‐informed drug development is increasingly integrated across the drug development continuum, enabling more efficient, cost‐effective, and targeted trials while reducing reliance on animal studies. Achieving pharmacoequity requires not only equitable access to medicines but also to the data and knowledge that inform drug development and regulatory ...
Shakir Atoyebi   +6 more
wiley   +1 more source

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission.

open access: yesPLoS Pathogens, 2015
Vaginal HIV transmission accounts for the majority of new infections worldwide. Currently, multiple efforts to prevent HIV transmission are based on pre-exposure prophylaxis with various antiretroviral drugs.
Martina Kovarova   +14 more
doaj   +1 more source

Virtual Screening of candidate Bio-actives from selected medicinal plants against rilpivirine resistance in HIV [PDF]

open access: yesE3S Web of Conferences
HIV, the causative virus of AIDS, has posed a severe threat to global health for an extensiveperiod. Recent statistics show the magnitude of this challenge, with approximately 2.4 million people inIndia living with HIV, along with 41.97 thousand deaths ...
Kumar Anish   +4 more
doaj   +1 more source

Mechanistic Modeling of Maternal Lymphoid and Fetal Plasma Antiretroviral Exposure During the Third Trimester

open access: yesFrontiers in Pediatrics, 2021
Pregnancy-induced changes in plasma pharmacokinetics of many antiretrovirals (ARV) are well-established. Current knowledge about the extent of ARV exposure in lymphoid tissues of pregnant women and within the fetal compartment is limited due to their ...
Babajide Shenkoya   +7 more
doaj   +1 more source

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