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Long-Acting Reversible Contraception [PDF]

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2017
Unwanted pregnancy is a major public health problem both in developed and developing countries. Although the reduction in the rates of these pregnancies requires multifactorial approaches, increasing access to long-acting contraceptive methods can ...
Rogerio Bonassi Machado   +8 more
doaj   +12 more sources

Easing the burden: exploring the role of long-acting testosterone formulations in gender-affirming care [PDF]

open access: yesFrontiers in Public Health
IntroductionLong-acting testosterone formulations are essential but infrequently used for gender affirmation. Although not FDA approved in the United States for gender dysphoria, testosterone undecanoate is a long-acting testosterone formulation ...
Rahil Hudda   +5 more
doaj   +2 more sources

Challenges of Current Anticancer Treatment Approaches with Focus on Liposomal Drug Delivery Systems

open access: yesPharmaceuticals, 2021
According to a 2020 World Health Organization report (Globocan 2020), cancer was a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020.
Vijay Gyanani   +2 more
doaj   +1 more source

Real-life efficacy and satisfaction of long-acting ART Cabotegravir-Rilpivirine in HIV-infected individuals [PDF]

open access: yesInfectious Diseases and Tropical Medicine, 2023
OBJECTIVE: Switching from oral anti-retroviral therapy (ART) to intramuscular administration of Cabotegravir-Rilpivirine (CAB+RPV) has been observed to decrease the number of pills that patients need to take, enhance patient satisfaction, and promote ...
S. Spampinato   +8 more
doaj   +1 more source

Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations

open access: yesPharmaceutics, 2023
Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported here.
Paul Curley   +16 more
doaj   +1 more source

Understanding the role of endothelial cells in brain tumor formation and metastasis: a proposition to be explored for better therapy

open access: yesJournal of the National Cancer Center, 2023
Glioblastoma is one of the most devastating central nervous system disorders. Being a highly vascular brain tumor, it is distinguished by aberrant vessel architecture.
Tejas Girish Agnihotri   +6 more
doaj   +1 more source

Pharmacological and toxicological studies of a novel goserelin acetate extended-release microspheres in rats

open access: yesFrontiers in Pharmacology, 2023
LY01005 is an investigational new drug product of goserelin acetate which is formulated as extended-release microspheres for intramuscular injection.
Mao Yutong   +11 more
doaj   +1 more source

Long-Acting Growth Hormone [PDF]

open access: yesPediatric Drugs, 2013
Human growth hormone (GH) is a 22 kDa protein synthesized and secreted in the anterior pituitary gland. GH synthesis and release is induced by hypothalamic GHreleasing hormone (GHRH) and ghrelin and attenuated by somatostatin and negative feedback by insulin-like growth factor (IGF)-I [1].
Höybye, Charlotte   +1 more
openaire   +3 more sources

Long-Acting Hormonal Contraception [PDF]

open access: yesWomen's Health, 2015
Today, a new category of fertility-regulating agents has been created: long-acting, reversible hormonal contraceptives; they minimize compliance, while maximize effectiveness. They comprise subdermal implants and intrauterine devices. Other long-acting agents exist, such as Depo Provera and Noristerat.
Giuseppe Benagiano   +2 more
openaire   +3 more sources

Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2

open access: yesCommunications Biology, 2021
Song et al describe and identify monoclonal antibodies that target the SARSCoV-2 Spike protein, including CA521FALA, which demonstrated neutralising potential in vivo and in vitro.
Deyong Song   +22 more
doaj   +1 more source

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