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Long-Acting Reversible Contraception [PDF]
Unwanted pregnancy is a major public health problem both in developed and developing countries. Although the reduction in the rates of these pregnancies requires multifactorial approaches, increasing access to long-acting contraceptive methods can ...
Rogerio Bonassi Machado +8 more
doaj +12 more sources
Easing the burden: exploring the role of long-acting testosterone formulations in gender-affirming care [PDF]
IntroductionLong-acting testosterone formulations are essential but infrequently used for gender affirmation. Although not FDA approved in the United States for gender dysphoria, testosterone undecanoate is a long-acting testosterone formulation ...
Rahil Hudda +5 more
doaj +2 more sources
Challenges of Current Anticancer Treatment Approaches with Focus on Liposomal Drug Delivery Systems
According to a 2020 World Health Organization report (Globocan 2020), cancer was a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020.
Vijay Gyanani +2 more
doaj +1 more source
Real-life efficacy and satisfaction of long-acting ART Cabotegravir-Rilpivirine in HIV-infected individuals [PDF]
OBJECTIVE: Switching from oral anti-retroviral therapy (ART) to intramuscular administration of Cabotegravir-Rilpivirine (CAB+RPV) has been observed to decrease the number of pills that patients need to take, enhance patient satisfaction, and promote ...
S. Spampinato +8 more
doaj +1 more source
Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations
Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported here.
Paul Curley +16 more
doaj +1 more source
Glioblastoma is one of the most devastating central nervous system disorders. Being a highly vascular brain tumor, it is distinguished by aberrant vessel architecture.
Tejas Girish Agnihotri +6 more
doaj +1 more source
LY01005 is an investigational new drug product of goserelin acetate which is formulated as extended-release microspheres for intramuscular injection.
Mao Yutong +11 more
doaj +1 more source
Long-Acting Growth Hormone [PDF]
Human growth hormone (GH) is a 22 kDa protein synthesized and secreted in the anterior pituitary gland. GH synthesis and release is induced by hypothalamic GHreleasing hormone (GHRH) and ghrelin and attenuated by somatostatin and negative feedback by insulin-like growth factor (IGF)-I [1].
Höybye, Charlotte +1 more
openaire +3 more sources
Long-Acting Hormonal Contraception [PDF]
Today, a new category of fertility-regulating agents has been created: long-acting, reversible hormonal contraceptives; they minimize compliance, while maximize effectiveness. They comprise subdermal implants and intrauterine devices. Other long-acting agents exist, such as Depo Provera and Noristerat.
Giuseppe Benagiano +2 more
openaire +3 more sources
Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2
Song et al describe and identify monoclonal antibodies that target the SARSCoV-2 Spike protein, including CA521FALA, which demonstrated neutralising potential in vivo and in vitro.
Deyong Song +22 more
doaj +1 more source

