Results 11 to 20 of about 823,716 (355)

Pharmacological Characterization of Toludesvenlafaxine as a Triple Reuptake Inhibitor

open access: yesFrontiers in Pharmacology, 2021
Toludesvenlafaxine hydrochloride dihydrate is a novel chemical entity and a potential triple monoamine reuptake inhibitor. This study characterized the in vitro triple reuptake inhibition activity, antidepressant-like activity in animals, and ...
Haibo Zhu   +9 more
doaj   +1 more source

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]

open access: yes, 2014
The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard   +4 more
core   +13 more sources

Long‐acting growth hormone in 2022

open access: yesPediatric Investigation, 2023
After the isolation of pituitary growth hormone (GH) in 1957, this form of GH, always in limited supply, was the only drug available for the treatment of GH deficiency.
Margaret Steiner   +2 more
doaj   +1 more source

Long-acting microneedle formulations

open access: yesAdvanced Drug Delivery Reviews, 2023
The minimally-invasive and painless nature of microneedle (MN) application has enabled the technology to obviate many issues with injectable drug delivery. MNs not only administer therapeutics directly into the dermal and ocular space, but they can also control the release profile of the active compound over a desired period.
Lalitkumar K. Vora   +13 more
openaire   +4 more sources

Clinical Effectiveness and Pharmacokinetics of Dalbavancin in Treatment-Experienced Patients with Skin, Osteoarticular, or Vascular Infections

open access: yesPharmaceutics, 2022
Dalbavancin (DBV) is a lipoglycopeptide approved for the treatment of Gram-positive infections of the skin and skin-associated structures (ABSSSIs). Currently, its off-label use at different dosages for other infections deserves attention.
Giacomo Stroffolini   +12 more
doaj   +1 more source

Long-acting antiretroviral therapy [PDF]

open access: yesNature Materials, 2020
Nanoformulations of cabotegravir prodrugs have been developed to prolong the pharmacokinetics of the antiretroviral agent. They can be present in the plasma of mice and non-human primates for a year following a single injection.
Vicente Soriano   +2 more
openaire   +2 more sources

Long-acting reversible contraception [PDF]

open access: yesBritish Journal of General Practice, 2013
I would like to draw the attention of your readers to the conclusions of a paper recently published in the Journal of Family Planning and Reproductive Healthcare ,1 the conclusion of which is that …
openaire   +4 more sources

Ultra-high-performance liquid chromatography for the determination of exenatide in monkey plasma by tandem quadrupole mass spectrometry

open access: yesJournal of Pharmaceutical Analysis, 2013
A highly sensitive ultra-high-performance liquid chromatographic–tandem mass spectrometry (UPLC/MS/MS) method was developed for the quantification of the synthetic peptide drug of exenatide in monkey plasma.
Jin-Feng Zhang   +9 more
doaj   +1 more source

Long acting growth hormone (LAGH), an update

open access: yesFrontiers in Pediatrics, 2023
In 1957, Maurice Raben at Yale was able to isolate and purify growth hormone from cadaveric pituitary glands. Pituitary growth hormone was the only way to treat children with growth hormone (GH) deficiency, until 1985 when recombinant GH became available
Margaret Steiner Grillo   +2 more
doaj   +1 more source

Condom use and incident sexually transmitted infection after initiation of long-acting reversible contraception [PDF]

open access: yes, 2017
Background Use of more effective contraception may lead to less condom use and increased incidence of sexually transmitted infection. Objective The objective of this study was to compare changes in condom use and incidence of sexually transmitted ...
Klugman, Jessica B.   +3 more
core   +1 more source

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