Results 21 to 30 of about 823,716 (355)

Optimization, validation and application of an assay for the activity of HMG-CoA reductase in vitro by LC–MS/MS

open access: yesJournal of Pharmaceutical Analysis, 2015
A stable HMG-CoA reductase (HMGR) reaction in vitro was developed by a sensitive, selective and precise liquid chromatography–tandem mass spectrometry (LC–MS/MS) method.
Jing Wang   +7 more
doaj   +1 more source

Long-Acting Reversible Contraception

open access: yesObstetrics & Gynecology, 2022
Long-acting reversible contraceptive (LARC) methods are effective options for pregnancy prevention. Currently available products in the United States include an etonogestrel implant, a copper intrauterine device (IUD), and several levonorgestrel IUDs. With increasing prevalence and duration of use, our understanding of efficacy, risks, and benefits has
Baker, Courtney C, Creinin, Mitchell D
openaire   +4 more sources

Pasireotide Long-Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism [PDF]

open access: yes, 2017
BACKGROUND: Long‐term medical management of hypersomatotropism (HS) in cats has proved unrewarding. Pasireotide, a novel somatostatin analogue, decreases serum insulin‐like growth factor 1 (IGF‐1) and improves insulin sensitivity in cats with HS when ...
Abraham   +43 more
core   +3 more sources

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD : current evidence and future prospects [PDF]

open access: yes, 2019
Long-acting bronchodilators are the cornerstone of pharmacologic treatment of chronic obstructive pulmonary disease (COPD). Spiolto (R) or Stiolto (R) is a fixed-dose combination (FDC) containing two long-acting bronchodilators, the long-acting ...
Brusselle, Guy, Derom, Eric, Joos, Guy
core   +1 more source

New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma [PDF]

open access: yes, 2017
Introduction: Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-acting beta2-agonist (LABA) are the preferred long-term treatment for adults and adolescents with symptomatic asthma.
Thomson, Neil C.
core   +1 more source

Inhaled corticosteroids versus long-acting beta -agonists for chronic obstructive pulmonary disease (Review). [PDF]

open access: yes, 2011
Long-acting beta(2)-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler.
Agarwal   +105 more
core   +2 more sources

Effect of long-acting injectable paliperidone 3 monthly and aripiprazol 1 monthly on hospitalization rate in a first-episode psychosis

open access: yesEuropean Psychiatry, 2021
Introduction Long-acting injectable antipsychotics (LAIs) can reduce relapse and hospitalization risk but they are not widely used in first psychotic episode (FEP) patientes. Objectives To examine the effcacy of two of the most used second generation
P. Gil Lopez   +3 more
doaj   +1 more source

Long-acting reversible contraception use among residents in obstetrics/gynecology training programs [PDF]

open access: yes, 2017
Background: The objective of the study was to estimate the personal usage of long-acting reversible contraception (LARC) among obstetrics and gynecology (Ob/Gyn) residents in the United States and compare usage between programs with and without a Ryan
Maddipati, Ragini   +4 more
core   +2 more sources

Use of short‐acting vs. long‐acting loop diuretics after heart failure hospitalization

open access: yesESC Heart Failure, 2022
Aims Furosemide, a short‐acting loop diuretic (SD), is the dominant agent prescribed for heart failure (HF) in clinical practice. However, accumulating data suggests that long‐acting loop diuretics (LD), such as torsemide or azosemide, might have more ...
Shohei Imaeda   +11 more
doaj   +1 more source

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]

open access: yes, 2015
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC   +6 more
core   +1 more source

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