Results 31 to 40 of about 17,231 (260)
Study of cascade ring-closing metathesis reactions en route to an advanced intermediate of Taxol [PDF]
, 2016 A highly functionalized intermediate in the synthesis of Taxol has been synthesized, which features the tricyclic core and the required oxygen substituents at C1, C2, C7, C10 and C13. The key step, a ring-closing dienyne metathesis (RCDEYM) reaction, has
Letort, Aurélien +2 more
core +1 more source
Synthesis of Pentacycloundecane (PCUD) Based Spiro-Pyrano-Cage Framework via Ring-Closing Metathesis
Molbank, 2023 Here, we demonstrate a short synthetic route to pyrano cage systems containing pentacycloundecane units by employing ring-closing metathesis (RCM) as a key step.
Sambasivarao Kotha +2 more
doaj +1 more source
Olefin metathesis in nano-sized systems
Beilstein Journal of Organic Chemistry, 2011 The interplay between olefin metathesis and dendrimers and other nano systems is addressed in this mini review mostly based on the authors’ own contributions over the last decade.
Didier Astruc +7 more
doaj +1 more source
Synthesis of Model BC Bicycles of Taxol Using C10-C11 Ring-Closing Metathesis Strategy [PDF]
, 2006 6 pagesInternational audienceModel BC ring-systems of taxol 23b and 28b, which lack an oxygenated substituent at C7, have been efficiently synthesized.
Ma, Cong +3 more
core +3 more sources
Beilstein Journal of Organic Chemistry, 2018 The metathesis of norbornene derivatives with alkynyl side-chain with Grubbs’ ruthenium alkylidine as catalyst has been investigated with the objective of constructing condensed polycyclic structures.
Ritabrata Datta, Subrata Ghosh
doaj +1 more source
Chemistry, 2022 Two new ruthenium complexes with chelating-ether benzylidene ligands bearing a furan moiety were synthesized and characterized, including X-ray crystallography.
Maryana Nadirova +3 more
doaj +1 more source
Synthesis and Activity of Six-Membered Cyclic Alkyl Amino Carbene–Ruthenium Olefin Metathesis Catalysts [PDF]
, 2020 Ru–cyclic alkyl amino carbene (Ru–CAAC) olefin metathesis catalysts perform extraordinarily in metathesis macrocyclization and ethenolysis, but previous studies have been limited to the use of five-membered CAAC (CAAC-5) ligands.
Grubbs, Robert H. +4 more
core
Z-Selective Olefin Metathesis on Peptides: Investigation of Side-Chain Influence, Preorganization, and Guidelines in Substrate Selection [PDF]
, 2014 Olefin metathesis has emerged as a promising strategy for modulating the stability and activity of biologically relevant compounds; however, the ability to control olefin geometry in the product remains a challenge.
Grubbs, Robert H. +2 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2015 We demonstrate a new synthetic strategy to cyclophanes containing thiophene and indole moieties via Grignard addition, Fischer indolization and ring-closing metathesis as key steps.
Sambasivarao Kotha +2 more
doaj +1 more source
Design of Heterogeneous Hoveyda–Grubbs Second-Generation Catalyst–Lipase Conjugates
Molecules, 2016 Heterogeneous catalysts have been synthesized by the conjugation of Hoveyda–Grubbs second-generation catalyst with a lipase. The catalytic properties of the organometallic compound in solution were firstly optimized, evaluating the activity of Ru in the ...
Anthony Neville +2 more
doaj +1 more source