Ruthenium Olefin Metathesis Catalysts Bearing an N-Fluorophenyl-N-Mesityl-Substituted Unsymmetrical N-Heterocyclic Carbene [PDF]
, 2007 Two new ruthenium-based olefin metathesis catalysts, each bearing an unsymmetrical N-heterocyclic carbene ligand, have been synthesized and fully characterized.
Grubbs, Robert H. +1 more
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Halide exchanged Hoveyda-type complexes in olefin metathesis
Beilstein Journal of Organic Chemistry, 2010 The aims of this contribution are to present a straightforward synthesis of 2nd generation Hoveyda-type olefin metathesis catalysts bearing bromo and iodo ligands, and to disclose the subtle influence of the different anionic co-ligands on the catalytic ...
Julia Wappel +6 more
doaj +1 more source
Study of cascade ring-closing metathesis reactions en route to an advanced intermediate of Taxol [PDF]
, 2016 A highly functionalized intermediate in the synthesis of Taxol has been synthesized, which features the tricyclic core and the required oxygen substituents at C1, C2, C7, C10 and C13. The key step, a ring-closing dienyne metathesis (RCDEYM) reaction, has
Letort, Aurélien +2 more
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Recent applications of ring-rearrangement metathesis in organic synthesis
Beilstein Journal of Organic Chemistry, 2015 Ring-rearrangement metathesis (RRM) involves multiple metathesis processes such as ring-opening metathesis (ROM)/ring-closing metathesis (RCM) in a one-pot operation to generate complex targets.
Sambasivarao Kotha +4 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2019 A novel and efficient approach to the synthesis of 2-vinylbenzylamines is reported. This involves obtaining 2-vinylbenzylamine ligands from tetrahydroisoquinoline by alkylation and reduction followed by the Hofmann cleavage.
Kirill B. Polyanskii +6 more
doaj +1 more source
Bidentate N,O-prolinate ruthenium benzylidene catalyst highly active in RCM of disubstituted dienes [PDF]
, 2007 The synthesis of a bidentate N,O-prolinate ruthenium benzylidene from commercially available starting materials and its activity in ring-closing metathesis of functionalized disubstituted dienes at 30 °C is ...
Grubbs, Robert H., Samec, Joseph S. M.
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First Total Synthesis of Cryptopyranmoscatone A3 and Cryptopyranmoscatone B4
SynOpen, 2018 The first total synthesis of cryptopyranmoscatones A3 and B4 has been accomplished from d-ribose or but-3-ynol. The key steps involved in the synthesis are oxa-Michael addition, highly diastereoselective Brown allylation, and ring closing metathesis ...
A. Maheswara Reddy, Gowravaram Sabitha
doaj +1 more source
Highly Active Water-Soluble Olefin Metathesis Catalyst [PDF]
, 2006 A novel water-soluble ruthenium olefin metathesis catalyst supported by a poly(ethylene glycol) conjugated saturated 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ligand is reported.
Grubbs, Robert H., Hong, Soon Hyeok
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A New Variant of Fused Cyclic Ether Synthesis Based on Ireland-Claisen Rearrangement and RCM
Natural Product Communications, 2013 A new variant of fused cyclic ether synthesis based on Ireland-Claisen rearrangement and ring-closing olefin metathesis (RCM) was developed. The Ireland-Claisen rearrangement and ring-closing olefin metathesis (RCM) was developed.
Daisuke Domon +5 more
doaj +1 more source
Rapid syntheses of difluorinated dihydropyrans [PDF]
, 2000 A very short reaction sequence opens with metal-mediated addition of commercial bromodifluoropropene to aldehydes; allylation under phase transfer catalysed conditions sets the stage for a ring closing metathesis (RCM) in the presence of commercial ...
Percy, Jonathan, Pintat, Stephane
core +1 more source