Results 181 to 190 of about 859,806 (359)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Stepwise B[triple bond, length as m-dash]N bond cleavage by isocyanides: access to the 3-azaborole structural motif. [PDF]

Chem Sci
Xiang L, Kwan KH, Jing Y, Wang J, Matler A, Chen X, Lin Z, Ye Q.   +7 more
europepmc   +1 more source

The Palladium/Norbornene‐Catalyzed Annulation Chemistry: Rapid Access to Diverse Ring Structures [PDF]

Mark Lautens, Xavier Abel‐Snape
openalex   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Data for: Tunable silicone elastomers through PDMS ring network design and post-curing chemistry

Frederikke Bahrt Madsen
openalex   +1 more source

Osmathiazole Ring: Extrapolation of an Aromatic Purely Organic System to Organometallic Chemistry

, 2023
Marı́a L. Buil, Miguel A. Esteruelas, Enrique Oñate, Nieves R. Picazo   +3 more
openalex   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Stretchable cyclodextrin slide-ring copolymer self-generating hydrogels for high-performance flexible electronics. [PDF]

Chem Sci
Pan X, Wang B, Yu XY, Yue JL, Zhang X, Zhang C, Zhang YM, Chen Y, Liu Y.   +8 more
europepmc   +1 more source

Aromatic Rings Commonly Used in Medicinal Chemistry: Force Fields Comparison and Interactions With Water Toward the Design of New Chemical Entities

, 2018
Marcelo D. Polêto, Victor H. Rusu, Bruno Iochins Grisci, Márcio Dorn, Roberto D. Lins, Hugo Verli   +5 more
openalex   +1 more source

Synthesis, structure, and chemistry of selenium-containing four-membered rings [PDF]

, 2005
Eric Block, Evgeny V. Dikarev, Jin Jin, Bo Li, Marina A. Petrukhina, Shaozhong Zhang   +5 more
openalex   +1 more source