Results 201 to 210 of about 859,806 (359)

The acid test: the chemistry of carboxylic acid functionalised {Cr₇Ni} rings

, 2013
George F. S. Whitehead, Jesús Ferrando‐Soria, Lorna G. Christie, Nicholas F. Chilton, Grigore A. Timco, Fabrizio Moro, Richard E. P. Winpenny   +6 more
openalex   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Hybrid benzylidene thiazolidine-2,4-diones as potent apoptosis-inducing anticancer agents: design-driven optimization, cytotoxic profiling, and mechanistic validation in prostate cancer. [PDF]

RSC Adv
Shaaban S, Hawas SS, Sharaky M, Ba-Ghazal H, Elmaaty AA, Alomari KB, Alaasar M, Elsharif AM, Alatawi FS, Mohamed MA, Al Khatib AO, Al-Karmalawy AA.   +11 more
europepmc   +1 more source

XXXI.—Contribution to the chemistry of “Fairy Rings.” [PDF]

J. Chem. Soc., Trans., 1883
Lawes, J. B., Gilbert, J. H., Warington, R.   +2 more
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Synthesis of bacteriochlorophyll <i>a</i>. [PDF]

Chem Sci
Chung DTM, Nguyen KC, Liu Y, Lindsey JS.
europepmc   +1 more source

New Aspects in the Chemistry of Silaaromatic Compounds and Coordination Chemistry Based on SiC5 Ring Skeletons

, 2010
Yusuke Tanabe
openalex   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Manifestations of Boron-Alkali Metal and Boron-Alkaline-Earth Metal Romances. [PDF]

Acc Chem Res
Cui ZH, Cui LJ, Barroso J, Guo JC, Zhai HJ, Pan S, Merino G.   +6 more
europepmc   +1 more source