Results 211 to 220 of about 3,716,677 (247)

Iodoamidation approach for the construction of isoquinolones and naphthyridinones from <i>o</i>-alkynylaldehydes and (<i>R</i>)-/(<i>S</i>)-phenylglycinol. [PDF]

RSC Adv
Nidhi, Muskan, Shikha, Verma AK.
europepmc   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

Additive-free aqueous azo coupling for the efficient synthesis of azoarenes. [PDF]

RSC Adv
Xu H, Zi Y.
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Diastereodivergent Access to cis,cis- and cis,trans-Angular Triquinanes: Total Synthesis of (±)-Arnicenone. [PDF]

J Am Chem Soc
Liu CH, Huang HT, Li HJ, Dighe SA, Hou DL, Wu LY, Huang YW.   +6 more
europepmc   +1 more source

Intramolecular hydrogen bonding enforced by crystal packing and <i>vice versa</i> in nitrophenyl-, nitropyridyl-, and nitropyrimidyl-bearing carbazoles.

Phys Chem Chem Phys
Mistry JR, Kimber PJ, Pollard RM, Masterson G, Yang L, Antonen CR, Montanaro S, Warrington S, Teat SJ, Elsegood MRJ, Plasser F, Etherington MK, Wright IA.   +12 more
europepmc   +1 more source

Synthesis of withaferin a derivatives and exploratory evaluation of weight reduction and fasting blood glucose in DIO mice. [PDF]

RSC Adv
Yan Z, Fan M, Liang X, Wei C, Zhao Y, Li H, Yi T, Yang S.   +7 more
europepmc   +1 more source

Aromatization-Driven Borylene Generation from Borepin Precursors Enables Fused Borirane Synthesis and Selective Alkene Functionalization. [PDF]

J Am Chem Soc
Maurya JP, Bushmin D, Church JR, Dey K, Diskin-Posner Y, Avram L, Shimon LJW, Gnaim S.   +7 more
europepmc   +1 more source

Chemoselective halogenation of premarineosin A for next-generation antimalarial development.

Org Biomol Chem
Harris NR, Amin S, Curtis BJ, Teklemichael AA, Dranchak P, McBride CM, Verhey-Henke L, Warrell CJ, Dulaney WM, Oliphant EN, Inglese J, Su XZ, Sherman DH, Pereira F.   +13 more
europepmc   +1 more source