Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Attractive and simple synthesis route from benzil to two different types of amino acid-derived imidazoles: first preliminary results. [PDF]
RSC AdvFerrer A +6 more
europepmc +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
The effect of substitution on the unimolecular reaction rates of stabilized Criegee intermediates.
Phys Chem Chem PhysKoskinen A +3 more
europepmc +1 more source
Melifoliox B, a novel phloroglucin derivative isolated from <i>Melicope barbigera</i> (Rutaceae) and synthesis of new oxidation products from melifoliones A and B. [PDF]
Beilstein J Org ChemWeber H +7 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Molecular dynamics of bicyclo[2.2.0]hex-2-ene ring opening and its polar derivative: allowed <i>vs.</i> forbidden pathways. [PDF]
Chem SciQin Z, Zhou Q, Wu RK, Houk KN.
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner +12 more
wiley +1 more source
Arene activation via π-bond localization: concepts and opportunities. [PDF]
Beilstein J Org ChemMeiners P, Melder JJ, Morack T.
europepmc +1 more source
New Adventures in the Chemistry of Polycarboncyclic Ring Systems [PDF]
, 1997 Zhiming E. Dong
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