Enzymatic one-step ring contraction for quinolone biosynthesis [PDF]
Nature Communications, 2018 Viridicatin is a fungal alkaloid. Here, the authors identify and characterize the cyclopenase that catalyzes the last step of its biosynthesis in Aspergillus nidulans, the conversion of cyclopenin to viridicatin, and find that the reaction proceeds via ...
Shinji Kishimoto +7 more
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Nucleophile-induced ring contraction in pyrrolo[2,1-c][1,4]benzothiazines: access to pyrrolo[2,1-b][1,3]benzothiazoles [PDF]
Beilstein Journal of Organic Chemistry, 2023 Pyrrolo[2,1-b][1,3]benzothiazoles are an important class of fused sulfur and nitrogen-containing heterocycles intensively studied in medicinal chemistry and pharmacology.
Ekaterina A. Lystsova +3 more
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Pyrrolidine synthesis via ring contraction of pyridines [PDF]
Nature CommunicationsA ring contraction of easily available cyclic compounds to smaller cycles that are valuable but difficult to synthetically access is one of important skeletal editing strategies.
Ryoga Ueno, Shohei Hirano, Jun Takaya
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Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction [PDF]
eLife, 2016 Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown ...
Junqi Huang +9 more
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Ring contraction and ring expansion reactions in terpenoid biosynthesis and their application to total synthesis [PDF]
Beilstein Journal of Organic ChemistryTerpenoids exhibit remarkable structural diversity, including highly complex ring-expanded or contracted carbocyclic skeletons. This review aims to explore intriguing examples of such ring-size alterations in all aspects of terpenoid synthesis.
Nicolas Kratena +2 more
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Myo2p is the major motor involved in actomyosin ring contraction in fission yeast. [PDF]
Curr Biol, 2017 Cytokinesis in many eukaryotes requires an actomyosin-based contractile ring [1]. In fission yeast, cytokinesis involves the type II myosins Myo2p and Myp2p and the type V myosin Myo51p [2]. A recent study by Laplante et al.
Zambon P +3 more
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Hypervalent Iodine–Mediated Ring Contraction Reactions [PDF]
Molecules, 2006 Hypervalent iodine reagents constitute a powerful tool in modern synthetic organic chemistry, promoting several important reactions. One such reaction is the ring contraction of cycloalkenes and cycloalkanones promoted by iodine(III) compounds, such as ...
Luiz F. Silva
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Chiral hypervalent iodine catalyzed stereoselective skeletal editing of pyrimidine fused heterocycles [PDF]
Nature CommunicationsIn the realm of molecular construction, the skeletal editing techniques of heterocyclic compounds demonstrate unique efficiency, particularly in synthesizing molecular structures that are challenging to obtain through traditional synthetic methods ...
Wen-Wu Sun, Yi-Bing Xie, Bin Wu
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Transformation of the cyclohexane ring to the cyclopentane fragment of biologically active compounds [PDF]
Beilstein Journal of Organic ChemistryThe review is devoted to strategies for contraction of six-membered cycles in the synthesis of functionalized cyclopentane/enones, which are biologically active compounds.
Natalya Akhmetdinova +2 more
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Известия высших учебных заведений: Геология и разведка, 2022 Introduction. The 60 m wide quartz dolerite stock, opened by a quarry, is heavily alternated by secondary processes, which makes it difficult to study.Aim.
V. A. Utenkov, A. V. Turov
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