Enzymatic one-step ring contraction for quinolone biosynthesis [PDF]
Nature Communications, 2018 Viridicatin is a fungal alkaloid. Here, the authors identify and characterize the cyclopenase that catalyzes the last step of its biosynthesis in Aspergillus nidulans, the conversion of cyclopenin to viridicatin, and find that the reaction proceeds via ...
Shinji Kishimoto +7 more
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Hypervalent Iodine–Mediated Ring Contraction Reactions [PDF]
Molecules, 2006 Hypervalent iodine reagents constitute a powerful tool in modern synthetic organic chemistry, promoting several important reactions. One such reaction is the ring contraction of cycloalkenes and cycloalkanones promoted by iodine(III) compounds, such as ...
Luiz F. Silva
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Nucleophile-induced ring contraction in pyrrolo[2,1-c][1,4]benzothiazines: access to pyrrolo[2,1-b][1,3]benzothiazoles [PDF]
Beilstein Journal of Organic Chemistry, 2023 Pyrrolo[2,1-b][1,3]benzothiazoles are an important class of fused sulfur and nitrogen-containing heterocycles intensively studied in medicinal chemistry and pharmacology.
Ekaterina A. Lystsova +3 more
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Pyrrolidine synthesis via ring contraction of pyridines [PDF]
Nature CommunicationsA ring contraction of easily available cyclic compounds to smaller cycles that are valuable but difficult to synthetically access is one of important skeletal editing strategies.
Ryoga Ueno, Shohei Hirano, Jun Takaya
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Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction [PDF]
eLife, 2016 Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown ...
Junqi Huang +9 more
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Results in Chemistry, 2022 A silica gel supported Malaprade cleavage of methyl maslinoate (→3) followed by a titanium-on-graphite supported McMurry coupling was established to access a 2,12-terpenoid.
Sophie Hoenke, Immo Serbian, René Csuk
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Motor activity dependent and independent functions for Myosin II in cytokinesis contribute to actomyosin ring assembly and contraction in Schizosaccharomyces pombe [PDF]
, 2017 Cytokinesis depends on a contractile actomyosin ring in many eukaryotes [1, 2, 3]. Myosin II is a key component of the actomyosin ring, although whether it functions as a motor or as an actin cross-linker to exert its essential role is disputed [1, 4, 5].
Balasubramanian, Mohan K. +10 more
core +3 more sources
Ring contraction and ring expansion reactions in terpenoid biosynthesis and their application to total synthesis [PDF]
Beilstein Journal of Organic ChemistryTerpenoids exhibit remarkable structural diversity, including highly complex ring-expanded or contracted carbocyclic skeletons. This review aims to explore intriguing examples of such ring-size alterations in all aspects of terpenoid synthesis.
Nicolas Kratena +2 more
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In vitro assembly, positioning and contraction of a division ring in minimal cells [PDF]
Nature Communications, 2022 Constructing a minimal protein machinery for self-division of membrane compartments is a major goal of bottom-up synthetic biology. Here, authors achieved the assembly, placement and onset of contraction of a minimal division ring in lipid vesicles.
Shunshi Kohyama +2 more
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Deaminative ring contraction for the synthesis of polycyclic heteroaromatics: a concise total synthesis of toddaquinoline. [PDF]
Chem Sci, 2023 Kirkeby EK +3 more
europepmc +3 more sources