Results 61 to 70 of about 197,833 (262)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

2-Benzoyl-4-phenyl-1,2,5-thiadiazol-3(2H)-one 1,1-Dioxide

open access: yesMolbank
3,5-Diphenyl-4H-1,2,6-thiadiazin-4-one treated with meta-chloroperoxybenzoic acid undergoes an oxidative ring contraction to give 2-benzoyl-4-phenyl-1,2,5-thiadiazol-3(2H)-one 1,1-dioxide in a 29% yield, the structure of which is supported by single ...
Emmanouil Broumidis   +4 more
doaj   +1 more source

Modifications of Tutte–Grothendieck invariants and Tutte polynomials

open access: yesAKCE International Journal of Graphs and Combinatorics, 2020
Generalized Tutte–Grothendieck invariants are mappings from the class of matroids to a commutative ring that are characterized recursively by contraction–deletion rules. Well known examples are Tutte, chromatic, tension and flow polynomials.
Martin Kochol
doaj   +1 more source

Contractions of Lie algebras and algebraic groups [PDF]

open access: yes, 2007
Degenerations, contractions and deformations of various algebraic structures play an important role in mathematics and physics. There are many different definitions and special cases of these notions.
Burde, Dietrich
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Rearrangement of beta,gamma-unsaturated esters with thallium trinitrate: synthesis of indans bearing a beta-keto ester moiety

open access: yesJournal of the Brazilian Chemical Society, 2006
The rearrangement of beta,gamma-unsaturated esters, such as 2-(3,4-dihydronaphthalen-1-yl)-propionic acid ethyl ester, with thallium trinitrate (TTN) in acetic acid leads to 3-indan-1-yl-2-methyl-3-oxo-propionic acid ethyl ester in good yield, through a ...
Silva Jr. Luiz F.   +2 more
doaj  

A neoclerodane orthoester and other new neoclerodane diterpenoids from Teucrium yemense chemistry and effect on secretion of insulin

open access: yesScientific Reports, 2021
Teucrium yemense, a medicinal plant commonly grown in Saudi Arabia and Yemen, is traditionally used to treat infections, kidney diseases, rheumatism, and diabetes.
Mohammad Nur-e-Alam   +8 more
doaj   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki   +8 more
wiley   +1 more source

Bildung eines Azacyclols durch transanulare Ringkontraktion

open access: yesCHIMIA, 1988
Reaction of 3-dimethylamino-2,2-dimethyl-2H-azirine (1) with phthalimide (8) in polar solvents yields the (1:1)-adduct 2-dimethylamino-9b-hydroxy-3,3-dimethyl-5,9b-dihydro-3H-imidazo[2,1-a]isoindol-5-one (10).
Marlise Schläpfer-Dähler   +4 more
doaj   +1 more source

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