Explicit IMF B y -Dependence of Energetic Protons and the Ring Current. [PDF]
Geophys Res Lett, 2022 Holappa L, Buzulukova NY.
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Coherent ring-current migration of Mg-phthalocyanine probed by time-resolved X-ray circular dichroism. [PDF]
Chem Sci, 2022 Sun S, Yong H, Chen F, Mukamel S.
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Identification of ring current proton precipitation driven by scattering of electromagnetic ion cyclotron waves. [PDF]
Fundam Res, 2023 Ni B, Zhang Y, Gu X.
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
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Multipoint MMS observations of fine‐scale SAPS structure in the inner magnetosphere
Geophysical Research Letters, 2016 We present detailed observations of dynamic, fine‐scale inner magnetosphere‐ionosphere coupling at ∼3.9 RE in the Region 2 Birkeland field‐aligned current (FAC). We find that observed electrodynamic spatial/temporal scales are primarily characteristic of
P. J. Erickson +11 more
doaj +1 more source
Diagnosing Ring Current(s) in Figure-Eight Skeletons: A 3D Through-Space Conjugation in the Two-Loops Crossing. [PDF]
Org Lett, 2022 Wypych K +3 more
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
A New Mechanism for Early-Time Plasmaspheric Refilling: The Role of Charge Exchange Reactions in the Transport of Energy and Mass Throughout the Ring Current-Plasmasphere System. [PDF]
J Geophys Res Space Phys, 2022 Liu J, Ilie R, Borovsky JE, Liemohn MW.
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