Results 81 to 90 of about 380,163 (265)

Reduced Order Probabilistic Emulator of RAM‐SCB: Toward Non‐Linearity With Autoencoders

open access: yesSpace Weather
An accurate understanding of the Earth's ring current dynamics is integral to predicting the impacts of geomagnetic storms. We use physics‐based models to simulate the ring current such as the Ring‐current Atmosphere interactions Model with Self ...
Q. Al Shidi, P. M. Mehta
doaj   +1 more source

A missing dusk-side loss process in the terrestrial electron ring current. [PDF]

open access: yesSci Rep, 2023
Haas B   +4 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Observational evidence of ring current in the magnetosphere of Mercury. [PDF]

open access: yesNat Commun, 2022
Zhao JT   +11 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Geomagnetic response to solar and interplanetary disturbances

open access: yesJournal of Space Weather and Space Climate, 2013
The space weather discipline involves different physical scenarios, which are characterised by very different physical conditions, ranging from the Sun to the terrestrial magnetosphere and ionosphere.
Saiz Elena   +13 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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