Results 91 to 100 of about 359,552 (281)

Quantum Chemical Calculations on CHOP Derivatives—Spanning the Chemical Space of Phosphinidenes, Phosphaketenes, Oxaphosphirenes, and COP Isomers

open access: yesMolecules, 2018
After many decades of intense research in low-coordinate phosphorus chemistry, the advent of Na[OCP] brought new stimuli to the field of CHOP isomers and derivatives thereof.
Alicia Rey   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Investigation of the Consecutive Electron Transfer of Metalloporphyrin Species on the Simulative Cell Membrane by Thin Layer Cyclic Voltammetry

open access: yesInternational Journal of Electrochemical Science, 2016
Metalloporphyrin, which is the essential sites of electron transfer in biological system, can be investigated the electrochemical process on cell membrane.
Wenting Gu   +5 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Electrocatalysis of fuel cell reactions: Investigation of alternate electrolytes [PDF]

open access: yes
Oxygen reduction and transport properties of the electrolyte in the phosphoric acid fuel cell are studied. A theoretical expression for the rotating ring-disk electrode technique; the intermediate reaction rate constants for oxygen reduction on platinum ...
Chang, H. H., Chin, D. T., Hsueh, K. L.
core   +4 more sources

Tropospheric Degradation of Perfluorinated Aromatics: A Case of Hexafluorobenzene

open access: yesCroatica Chemica Acta, 2015
The major tropospheric removal process for hexafluorobenzene is its oxidation by hydroxyl (OH) radicals. However, there is no information on the reaction mechanism of this important process.
Goran Kovačević, Aleksandar Sabljić
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Coordination Chemistry of Glycolic Acid and Uranyl

open access: yesYuanzineng kexue jishu
Glycolic acid (α-hydroxyacetic acid, HA) is a simple, water-soluble carboxylic acid ligand commonly found in the environment. It can coordinate with metal ions through both its carboxyl and hydroxyl oxygen atoms.
ZENG Deli1, LIU Qian1, YANG Qi1, LI Jiale1, PU Tongkai1, YANG Suliang1, TIAN Guoxin1, 2
doaj   +1 more source

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