Results 71 to 80 of about 77,990 (262)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A database of steric and electronic properties of heteroaryl substituents

Scientific Data
Heteroaryl substituents are important building blocks of functionalized organic compounds in drug discovery, materials science, and catalysis. Quantitative descriptions of steric and electronic properties of heteroaryl substituents are essential in ...
Turki M. Alturaifi, Grace E. Scofield, Shengchun Wang, Peng Liu   +3 more
doaj   +1 more source

Self-Stabilizing Ring Orientation Using Constant Space

Information and Computation, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Quantum Chemical Calculations on CHOP Derivatives—Spanning the Chemical Space of Phosphinidenes, Phosphaketenes, Oxaphosphirenes, and COP⁻ Isomers

Molecules, 2018
After many decades of intense research in low-coordinate phosphorus chemistry, the advent of Na[OCP] brought new stimuli to the field of CHOP isomers and derivatives thereof.
Alicia Rey, Arturo Espinosa Ferao, Rainer Streubel   +2 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Quasi‐Constant Time Gap in Multiple Rings of Elves

Earth and Space Science
Abstract We present evidence that the time delay between the multiple rings of elves is not caused by the ground reflection of the electromagnetic pulse produced by intracloud lightning. To investigate temporal differences of multi‐elves, we analyzed data from four storms occurring at various times and distances from the Pierre Auger ...
A. Abdul Halim13, P. Abreu70, M. Aglietta53, 51, I. Allekotte1, K. Almeida Cheminant78, 77, A. Almela7, 12, R. Aloisio44, 45, J. Alvarez‐Muñiz76, A. Ambrosone44, J. Ammerman Yebra76, G. A. Anastasi, L. Anchordoqui83, B. Andrada7, L. Andrade Dourado44, 45, S. Andringa70, L. Apollonio58, 48, C. Aramo49, E. Arnone62, 51, J. C. Arteaga Velázquez66, P. Assis70, G. Avila11, E. Avocone56, 45, A. Bakalova31, F. Barbato44, 45, A. Bartz Mocellin82, J. A. Bellido13, C. Berat35, M. E. Bertaina62, 51, M. Bianciotto62, 51, P. L. Biermanna, V. Binet5, K. Bismark38, 7, T. Bister77, 78, J. Biteau36, i, J. Blazek31, J. Blümer40, M. Boháčová31, D. Boncioli56, 45, C. Bonifazi8, L. Bonneau Arbeletche22, N. Borodai68, J. Brackf, P. G. Brichetto Orchera7, F. L. Briechle41, A. Bueno75, S. Buitink15, M. Buscemi, 57, M. Büsken38, 7, A. Bwembya77, 78, K. S. Caballero‐Mora65, S. Cabana‐Freire76, L. Caccianiga58, 48, F. Campuzano6, J. Caraça‐Valente82, R. Caruso, A. Castellina53, 51, F. Catalani19, G. Cataldi47, L. Cazon76, M. Cerda10, B. Čermáková40, A. Cermenati44, 45, J. A. Chinellato22, J. Chudoba31, L. Chytka32, R. W. Clay13, A. C. Cobos Cerutti6, R. Colalillo59, 49, R. Conceição70, A. Condorelli36, G. Consolati48, 54, M. Conte55, 47, F. Convenga56, 45, D. Correia dos Santos27, P. J. Costa70, C. E. Covault81, M. Cristinziani43, C. S. Cruz Sanchez3, S. Dasso4, 2, K. Daumiller40, B. R. Dawson13, R. M. de Almeida27, E. ‐T. de Boone43, B. de Errico27, J. de Jesús7, 40, S. J. de Jong77, 78, J. R. T. de Mello Neto27, I. De Mitri44, 45, J. de Oliveira18, D. de Oliveira Franco42, F. de Palma55, 47, V. de Souza20, E. De Vito55, 47, A. Del Popolo, O. Deligny33, N. Denner31, L. Deval40, 7, A. di Matteo51, C. Dobrigkeit22, J. C. D’Olivo67, L. M. Domingues Mendes16, 70, Q. Dorosti43, J. C. dos Anjos16, R. C. dos Anjos26, J. Ebr31, F. Ellwanger40, M. Emam77, 78, R. Engel38, 40, I. Epicoco55, 47, M. Erdmann41, A. Etchegoyen7, 12, C. Evoli44, 45, H. Falcke77, 79 78, G. Farrar85, A. C. Fauth22, T. Fehler43, F. Feldbusch39, A. Fernandes70, B. Fick84, J. M. Figueira7, P. Filip38, 7, A. Filipčič74, 73, T. Fitoussi40, B. Flaggs87, T. Fodran77, M. Freitas70, T. Fujii86, h, A. Fuster7, 12, C. Galea77, B. García6, C. Gaudu37, P. L. Ghia33, U. Giaccari47, F. Gobbi10, F. Gollan7, G. Golup1, M. Gómez Berisso1, P. F. Gómez Vitale11, J. P. Gongora11, J. M. González1, N. González7, D. Góra68, A. Gorgi53, 51, M. Gottowik40, F. Guarino59, 49, G. P. Guedes23, E. Guido43, L. Gülzow40, S. Hahn38, P. Hamal31, M. R. Hampel7, P. Hansen3, V. M. Harvey13, A. Haungs40, T. Hebbeker41, A. Insolia, D. Martello55, A. Nucita55, L. Perrone55, V. Scherini55   +204 more
openaire   +8 more sources

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Investigation of the Consecutive Electron Transfer of Metalloporphyrin Species on the Simulative Cell Membrane by Thin Layer Cyclic Voltammetry

International Journal of Electrochemical Science, 2016
Metalloporphyrin, which is the essential sites of electron transfer in biological system, can be investigated the electrochemical process on cell membrane.
Wenting Gu, Wenjian Li, Ruiyuan Liu, Yin Qu, Libin Zhou, Xicun Dong   +5 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source