Results 81 to 90 of about 77,438 (264)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Investigation of the Consecutive Electron Transfer of Metalloporphyrin Species on the Simulative Cell Membrane by Thin Layer Cyclic Voltammetry

International Journal of Electrochemical Science, 2016
Metalloporphyrin, which is the essential sites of electron transfer in biological system, can be investigated the electrochemical process on cell membrane.
Wenting Gu, Wenjian Li, Ruiyuan Liu, Yin Qu, Libin Zhou, Xicun Dong   +5 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Coordination Chemistry of Glycolic Acid and Uranyl

Yuanzineng kexue jishu
Glycolic acid (α-hydroxyacetic acid, HA) is a simple, water-soluble carboxylic acid ligand commonly found in the environment. It can coordinate with metal ions through both its carboxyl and hydroxyl oxygen atoms.
ZENG Deli1, LIU Qian1, YANG Qi1, LI Jiale1, PU Tongkai1, YANG Suliang1, TIAN Guoxin1, 2
doaj   +1 more source

Picolinic acid promoted oxidative decarboxylation of phenylsulfinylacetic acid by Cr(VI)

Bulletin of the Chemical Society of Ethiopia, 2016
The kinetics and mechanism of picolinic acid promoted reaction of phenylsulfinylacetic acid (PSAA) with Cr(VI) was carried out in aqueous acetonitrile medium under pseudo first order conditions. The reaction follows Michaelis-Menten type of kinetics with
P. Subramaniam, N. T. Selvi
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Tropospheric Degradation of Perfluorinated Aromatics: A Case of Hexafluorobenzene

Croatica Chemica Acta, 2015
The major tropospheric removal process for hexafluorobenzene is its oxidation by hydroxyl (OH) radicals. However, there is no information on the reaction mechanism of this important process.
Goran Kovačević, Aleksandar Sabljić
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Potentiometric investigation of acid-base equilibria of two newv pyrimidine derivatives in various methanol–water media [PDF]

Journal of the Serbian Chemical Society, 2006
The acid-base properties of 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-one (L1) and 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-thione (L2) were investigated potentiometrically at an ionic strength of 0.10M(LiCl) in 19.8, 33.6 and 55.9 % (v/v) methanolâ ...
HASAN KILIÇ, BİROL ER
doaj  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source